5-Thio-D-glucose

CAS 20408-97-3C6H12O5SBiochemicals & Reagents

5-Thio-D-glucose (CAS: 20408-97-3, C6H12O5S, MW: 196.22) is a thiosugar analogue of D-glucose. It functions as a hexokinase inhibitor, making it valuable for controlling or reducing the rate of glycolysis in biological systems. This biochemical is primarily used in research settings to study metabolic pathways and cellular energy production. Tech Serve Solutions supplies this compound with a high purity, ensuring reliable results in experimental applications.

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5-Thio-D-glucose (C6H12O5S) — chemical structure, CAS 20408-97-3; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsCarbohydratesMonosaccharide

01 /Applications

Glycolysis Inhibition

5-Thio-D-glucose acts as a specific inhibitor of hexokinase, an enzyme crucial for the initial step of glycolysis. By inhibiting this enzyme, it effectively slows down the rate of glucose metabolism within cells.

Biochemical Research Tool

This thiosugar is employed in various biochemical and cell biology research studies. It allows scientists to investigate the role of glycolysis in cellular processes and disease states.

Metabolic Pathway Analysis

Researchers utilise 5-Thio-D-glucose to probe the intricacies of carbohydrate metabolism. Its ability to modulate glycolysis provides insights into cellular energy regulation and substrate utilisation.

02 /Properties

Molecular weight	196.22
Empirical formula	C6H12O5S
Assay	≥98.0% (HPLC)
Optical activity	[α]/D 220.0±5.0°, c = 1 in 0.1 M HCl
Application	5-Thio-D-glucose (Glc-5S), a thiosugar hexokinase inhibitor, is used to control/reduce the rate of glycolysis in vivo.
Melting point	135-138 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

20408-97-3

MDL number

MFCD00006663

Beilstein registry

1865193

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Thio-D-glucose used for?

5-Thio-D-glucose is primarily used as a hexokinase inhibitor to control or reduce the rate of glycolysis in biological research. It serves as a valuable tool for studying metabolic pathways and cellular energy regulation.

What is the CAS number and formula for 5-Thio-D-glucose?

The CAS number for 5-Thio-D-glucose is 20408-97-3, and its empirical formula is C6H12O5S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-Thio-D-glucose with a minimum assay of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 5-Thio-D-glucose be handled?

Appropriate handling requires the use of safety goggles and chemical-resistant gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling information. The WGK Germany classification is 3.

How is 5-Thio-D-glucose packed and shipped?

Tech Serve Solutions offers this compound in various pack sizes suitable for laboratory and research needs. It is available for export globally, adhering to all relevant shipping regulations for chemical compounds.

How can I request a sample or quote for 5-Thio-D-glucose?

To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or by direct inquiry, providing your specific requirements and shipping details.