5-Propyl-2-thiouracil
5-Propyl-2-thiouracil (CAS: 2954-52-1), a thiouracil derivative with the molecular formula C7H10N2OS and a molecular weight of 170.23 g/mol, is a biochemical reagent. It is primarily employed in scientific research to induce and investigate the mechanisms of hypothyroidism, focusing on thyroid hormone biosynthesis and gene regulation.
- IUPAC
- PTU

Induction of Hypothyroidism in Research Models
5-Propyl-2-thiouracil is utilised to experimentally induce a state of hypothyroidism in laboratory settings. This allows researchers to study the intricate mechanisms by which thyroid hormone biosynthesis and gene regulation are affected.
Thyroid Hormone Biosynthesis Studies
The compound serves as a tool to probe the processes involved in the synthesis of thyroid hormones. Its application helps elucidate the biochemical pathways and enzymatic activities critical for hormone production.
Gene Regulation Research
By inducing hypothyroidism, 5-Propyl-2-thiouracil facilitates research into the regulatory roles of thyroid hormones on gene expression. This aids in understanding cellular responses and metabolic control at a molecular level.
| Molecular weight | 170.23 |
|---|---|
| Empirical formula | C7H10N2OS |
| Assay | ≥98% |
| Application | 5-Propyl-2-thiouracil (PTU) is used to induce and study mechanisms of hypothyroidism at the levels of thyroid hormone biosynthesis and gene regulation. |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Propyl-2-thiouracil used for?
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5-Propyl-2-thiouracil is used in research to induce and study the mechanisms of hypothyroidism, particularly concerning thyroid hormone biosynthesis and gene regulation.
What are the CAS number and molecular formula for 5-Propyl-2-thiouracil?
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The CAS number for 5-Propyl-2-thiouracil is 2954-52-1, and its molecular formula is C7H10N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Propyl-2-thiouracil with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How should 5-Propyl-2-thiouracil be handled safely?
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5-Propyl-2-thiouracil is classified under GHS08 with a Warning signal word and carries the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment includes eyeshields, gloves, and a respirator (e.g., type N100 or P3). Handle in a well-ventilated area and follow all recommended safety precautions.
Is 5-Propyl-2-thiouracil a controlled substance?
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The provided data does not indicate that 5-Propyl-2-thiouracil is a controlled substance.
How is 5-Propyl-2-thiouracil packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures compliant packing and shipping of chemicals like 5-Propyl-2-thiouracil according to international regulations.
How can I request a quote or sample?
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To request a quote or sample for 5-Propyl-2-thiouracil, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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