Chloroform

CAS 67-66-3CHCl3Biochemicals & Reagents

Chloroform (CHCl3), CAS 67-66-3, is a volatile, colourless liquid with a sweet odour. It possesses a molecular weight of 119.38 g/mol. Historically recognised for its anaesthetic properties, its primary contemporary applications are as a solvent and reagent in chemical synthesis and laboratory research. Tech Serve Solutions supplies Chloroform with an assay of ≥99.5%, suitable for various analytical and synthetic procedures.

IUPAC: Methylidyne trichloride,Trichloromethane
Synonyms: TrichloromethaneMethylidyne trichloride

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Chloroform (CHCl3) — chemical structure, CAS 67-66-3; Life Science, fine chemical supplied by Tech Serve Solutions

Amber Glass BottlesBiochemicalsBiochemicals and ReagentsChloroformCore BioreagentsDNA & RNA PurificationGeneral ReagentsMolecular BiologyMolecular Biology ReagentsNanodisc Essentials

01 /Applications

Solvent in Organic Synthesis

Chloroform serves as a non-polar solvent in numerous organic reactions and extractions. Its ability to dissolve a wide range of organic compounds makes it valuable in laboratory settings for various synthetic procedures.

Reagent in Biochemical Research

It is utilised in specialised biochemical techniques such as Chromatin Isolation by RNA Purification (ChIRP). This application allows researchers to study RNA-chromatin interactions and map their genomic occupancy.

Laboratory Reagent

As a versatile laboratory reagent, chloroform is employed in analytical chemistry and research for its solvent properties and participation in specific chemical transformations.

02 /Properties

Molecular weight	119.38
Empirical formula	CHCl3
Assay	≥99.5%
Boiling point	60.5-61.5 °C(lit.)
Density	1.492 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.445(lit.)
Vapour pressure	160 mmHg (20 °C)
Melting point	−63 °C(lit.)
Vapour density	4.1 (vs air)
Contains / stabiliser	100-200 ppm amylenes as stabilizer
Application	Chromatin isolation by RNA purification (ChIRP). Ci C Chu, Jeffrey J Quinn, Howard Y HY Chang, Journal of Visualized Experiments 2012-01-01Chromatin isolation by RNA purification (ChIRP)Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.Ci C Chu, Kun K Qu, Franklin L FL Zhong, Steven E SE Artandi, Howard Y HY Chang, Molecular Cell 2011-11-18Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H361D
H373May cause damage to organs through prolonged exposure

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P281Use personal protective equipment as required
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
Transport (UN / ADR)	UN 1888 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-38-40-48/20/22
Safety statements (S)	36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

67-66-3

MDL number

MFCD00000826

PubChem substance

24892487

Beilstein registry

1731042

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chloroform (CAS 67-66-3) used for?

Chloroform is used as a solvent in organic synthesis, a reagent in biochemical research for techniques like Chromatin Isolation by RNA Purification (ChIRP), and a general laboratory reagent for analytical and synthetic procedures.

What is the CAS number and chemical formula for Chloroform?

The CAS number for Chloroform is 67-66-3, and its chemical formula is CHCl3.

What grade and purity does Tech Serve Solutions supply for Chloroform?

Tech Serve Solutions supplies Chloroform with an assay of ≥99.5%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.

How should Chloroform be handled safely?

Chloroform is harmful if swallowed or inhaled, causes skin irritation and serious eye irritation, may cause drowsiness or dizziness, and is suspected of causing cancer and genetic defects, and may damage fertility or the unborn child. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.

How is Chloroform shipped and exported by TSS?

Chloroform is typically supplied in amber glass bottles and is exported globally by Tech Serve Solutions in compliance with all relevant shipping and handling regulations for hazardous materials.