2-Chloro-5-chloromethylthiazole
2-Chloro-5-chloromethylthiazole (CAS: 105827-91-6, Formula: C4H3Cl2NS) is a halogenated heterocyclic compound with a molecular weight of 168.04 g/mol. It serves as a valuable building block in organic synthesis, particularly within the fields of chemical synthesis and the development of novel compounds. This thiazole derivative is crucial for introducing specific structural motifs in complex molecular architectures.
- IUPAC
- 2-Chloro-5-thiazolylmethyl chloride
- Synonyms
- 2-Chloro-5-thiazolylmethyl chloride

Organic Synthesis Intermediate
This compound is widely employed as an intermediate in the synthesis of various organic molecules. Its dichlorinated thiazole structure makes it suitable for diverse chemical transformations, enabling the construction of more complex chemical entities.
Pharmaceutical Research
2-Chloro-5-chloromethylthiazole can be utilised in the research and development of potential pharmaceutical agents. Its heterocyclic nature and reactive chlorine atoms offer avenues for creating compounds with targeted biological activities.
Agrochemical Development
The structural features of this thiazole derivative may lend themselves to the synthesis of novel agrochemicals. It can serve as a precursor for developing pesticides, herbicides, or fungicides.
| Molecular weight | 168.04 |
|---|---|
| Empirical formula | C4H3Cl2NS |
| Assay | ≥98.0% (HPLC) |
| Grade | analytical standard |
| Refractive index | n20/D 1.571 |
| Storage temperature | 2-8°C |



Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-chloromethylthiazole used for?
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2-Chloro-5-chloromethylthiazole is primarily used as a building block in organic synthesis, including pharmaceutical and agrochemical research and development.
What are the CAS number and chemical formula for 2-Chloro-5-chloromethylthiazole?
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The CAS number is 105827-91-6 and the chemical formula is C4H3Cl2NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-chloromethylthiazole with an assay of ≥98.0% (HPLC), specified as an analytical standard. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloro-5-chloromethylthiazole be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves. This compound is dangerous, causes severe skin burns and eye damage, may cause an allergic skin reaction, and is harmful if swallowed or inhaled. It is also toxic to aquatic life with long-lasting effects. Always consult the Safety Data Sheet (SDS) before use.
Is 2-Chloro-5-chloromethylthiazole a controlled substance?
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The provided data does not indicate that 2-Chloro-5-chloromethylthiazole is a controlled substance.
How is 2-Chloro-5-chloromethylthiazole packed and shipped?
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This chemical is typically stored at 2-8°C. Packing and shipping methods comply with international regulations for hazardous materials to ensure safe transport and export.
How can I request a sample or quote for 2-Chloro-5-chloromethylthiazole?
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Please contact the TSS sales team directly via our website or your dedicated account manager to request a sample or a quotation.
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