2-Chloro-5-(trifluoromethyl)pyridine
2-Chloro-5-(trifluoromethyl)pyridine (CAS: 52334-81-3), a halogenated pyridine derivative with the molecular formula C6H3ClF3N and a molecular weight of 181.54 g/mol, is a valuable building block in organic synthesis. Its structure, featuring both a chlorine atom and a trifluoromethyl group on the pyridine ring, allows for diverse chemical transformations. This compound finds utility in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical industries.
Pharmaceutical Intermediates
Utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethylpyridine moiety is a key structural component.
Agrochemical Development
Serves as a precursor for novel herbicides, insecticides, and fungicides, contributing to the development of advanced crop protection agents.
Materials Science
Incorporated into the design and synthesis of specialised polymers and functional materials requiring fluorinated heterocyclic units.
Organic Synthesis Research
Employed as a versatile reagent in academic and industrial research laboratories for the construction of complex organic molecules.
| Molecular weight | 181.54 |
|---|---|
| Empirical formula | C6H3ClF3N |
| Density | 1.417 g/mL at 25 °C(lit.) |
| Melting point | 32-34 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-(trifluoromethyl)pyridine used for?
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2-Chloro-5-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for the creation of pharmaceutical intermediates and agrochemicals. It is also employed in materials science research and general organic synthesis.
What is the CAS number and chemical formula for 2-Chloro-5-(trifluoromethyl)pyridine?
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The CAS number for 2-Chloro-5-(trifluoromethyl)pyridine is 52334-81-3, and its chemical formula is C6H3ClF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated. Please refer to the product's Certificate of Analysis for specific purity information.
How should 2-Chloro-5-(trifluoromethyl)pyridine be handled safely?
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2-Chloro-5-(trifluoromethyl)pyridine is classified as an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95 type recommended). Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Store in a well-ventilated place.
Is 2-Chloro-5-(trifluoromethyl)pyridine a controlled substance?
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The provided data does not indicate that 2-Chloro-5-(trifluoromethyl)pyridine is a controlled or scheduled substance.
How is 2-Chloro-5-(trifluoromethyl)pyridine packed, shipped, and exported?
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Tech Serve Solutions packages and exports chemicals in compliance with all relevant international shipping and hazardous goods regulations, ensuring secure and safe delivery worldwide.
How can I request a sample or quote for 2-Chloro-5-(trifluoromethyl)pyridine?
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To request a sample or a quotation for 2-Chloro-5-(trifluoromethyl)pyridine, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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