N-Nitroso-N-ethylurea
N-Nitroso-N-ethylurea (CAS 759-73-9), with the molecular formula C3H7N3O2 and a molecular weight of 117.11 g/mol, is a chemical compound used primarily in cancer research. It is known for its potent mutagenic and carcinogenic properties, making it a valuable tool for studying DNA damage and repair mechanisms in biological systems. Supplied as a solution in aqueous acetic acid.
- IUPAC
- ENU,N-Ethyl-N-nitrosourea
- Synonyms
- N-Ethyl-N-nitrosoureaENU
Mutagenesis Research
N-Nitroso-N-ethylurea is widely employed as a chemical mutagen in experimental studies. Its ability to induce genetic mutations allows researchers to investigate DNA repair pathways and the molecular basis of carcinogenesis.
Carcinogenesis Studies
Due to its established carcinogenic effects, N-Nitroso-N-ethylurea serves as a model compound for inducing tumours in laboratory animals. This facilitates the study of cancer development, progression, and potential therapeutic interventions.
Cell Biology Research
This compound is utilised in cell biology to explore the cellular responses to DNA damage. It aids in understanding mechanisms such as apoptosis, cell cycle arrest, and genomic instability.
| Molecular weight | 117.11 |
|---|---|
| Empirical formula | C3H7N3O2 |
| Storage temperature | −20°C |
| Contains / stabiliser | aqueous acetic acid as stabilizer |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H350May cause cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-61-20/21/22 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Nitroso-N-ethylurea used for?
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N-Nitroso-N-ethylurea (CAS 759-73-9) is primarily used in cancer research as a mutagen and carcinogen to study DNA damage, repair mechanisms, and tumour development in experimental models.
What is the CAS number and formula for N-Nitroso-N-ethylurea?
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The CAS number for N-Nitroso-N-ethylurea is 759-73-9, and its molecular formula is C3H7N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Nitroso-N-ethylurea in aqueous acetic acid as a stabilizer. The specific assay and purity are detailed in the product's Certificate of Analysis. It is not supplied as USP, BP, or EP grade.
What are the primary hazards associated with N-Nitroso-N-ethylurea?
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N-Nitroso-N-ethylurea is highly toxic and a suspected carcinogen and mutagen. It is harmful if swallowed, inhaled, or in contact with skin, and may cause genetic defects and cancer. Strict adherence to safety protocols is essential.
How is N-Nitroso-N-ethylurea shipped?
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N-Nitroso-N-ethylurea is shipped according to international regulations for hazardous materials, including UN 2811 classification. Please contact us for specific export and shipping details.
How can I request a sample or quote for N-Nitroso-N-ethylurea?
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To request a sample or quote for N-Nitroso-N-ethylurea, please use the 'Request a Quote' or 'Contact Us' form on our website, providing your details and the product CAS number (759-73-9).
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