N-Nitroso-N-methylurea
N-Nitroso-N-methylurea (CAS 684-93-5, C2H5N3O2, MW 103.08) is a potent alkylating agent supplied by TSS. This compound is primarily utilised in cancer research for its mutagenic and carcinogenic properties, enabling scientists to study DNA damage and repair mechanisms. It is also employed in cell biology studies for its ability to induce mutations, offering valuable insights into genetic processes. Supplied in aqueous acetic acid for stability.
- IUPAC
- MNU,N-Methyl-N-nitrosourea
- Synonyms
- MNUN-Methyl-N-nitrosourea
Cancer Research Agent
N-Nitroso-N-methylurea serves as a critical research tool in oncology. Its established mutagenic and carcinogenic properties allow researchers to investigate the mechanisms of cancer development and test potential therapeutic interventions.
Mutagenesis Studies
In cell biology and genetics, MNU is used to induce targeted mutations in experimental models. This enables the study of gene function, DNA repair pathways, and the effects of genetic alterations.
Carcinogenesis Research
The compound's reliable ability to cause cancer makes it invaluable for creating animal models of specific cancers, facilitating preclinical studies and drug discovery efforts.
| Molecular weight | 103.08 |
|---|---|
| Empirical formula | C2H5N3O2 |
| Storage temperature | 2-8°C |
| Contains / stabiliser | aqueous acetic acid as stabilizer |
Hazard statements
- H228Flammable solid
- H301Toxic if swallowed
- H350May cause cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P210Keep away from heat, sparks and open flames. No smoking
- P301IF SWALLOWED
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1325 4.1/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-61-25 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Nitroso-N-methylurea used for?
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N-Nitroso-N-methylurea (CAS 684-93-5) is primarily used in cancer research and cell biology for its mutagenic and carcinogenic properties, aiding in the study of DNA damage, repair mechanisms, and gene function.
What is the CAS number and formula for N-Nitroso-N-methylurea?
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The CAS number for N-Nitroso-N-methylurea is 684-93-5, and its molecular formula is C2H5N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Nitroso-N-methylurea as a research chemical. The specific assay and purity are available on the Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Nitroso-N-methylurea be handled safely?
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N-Nitroso-N-methylurea is a highly hazardous substance (Danger, H228-H301-H350-H360). Handle with extreme caution in a well-ventilated area or fume hood, wearing appropriate personal protective equipment including eyeshields, face shields, impermeable gloves, and respiratory protection (e.g., N100 respirator).
How is N-Nitroso-N-methylurea packed and shipped?
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N-Nitroso-N-methylurea is a flammable solid (UN 1325 4.1/PG 2). It is typically stored at 2-8°C and stabilised with aqueous acetic acid. Shipping and export are conducted in compliance with all relevant dangerous goods regulations.
How can I request a quote or sample for N-Nitroso-N-methylurea?
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To request a quote or a sample of N-Nitroso-N-methylurea, please contact our sales department through the TSS website or call us directly. Our team will be happy to assist you with your inquiry.
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