2-Chloro-5-chlorosulfonyl-4-fluorobenzoic acid
2-Chloro-5-chlorosulfonyl-4-fluorobenzoic acid (CAS: 264927-50-6), with the molecular formula ClC6H2(SO2Cl)(F)CO2H and a molecular weight of 273.07 g/mol, is a specialised organic compound. It serves as a key intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical sectors, due to its reactive functional groups. Its structure makes it valuable for introducing specific chemical moieties into more complex molecules during targeted syntheses.

Pharmaceutical Intermediate
This compound is utilised as a building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique combination of halogen and sulfonyl chloride functionalities allows for diverse chemical transformations essential for drug discovery and development.
Agrochemical Synthesis
It finds application in the development of novel agrochemicals, including herbicides and pesticides. The fluorinated aromatic structure can impart desirable properties such as increased efficacy and environmental stability to the final products.
Organic Synthesis Reagent
As a versatile organic building block, it is employed in various research and development projects requiring specific fluorinated aromatic structures with reactive sites for further chemical modification.
| Molecular weight | 273.07 |
|---|---|
| Linear formula | ClC6H2(SO2Cl)(F)CO2H |
| Assay | 98% |
| Melting point | 145-148 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 25-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-chlorosulfonyl-4-fluorobenzoic acid used for?
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This compound is primarily used as a key intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals, and as a versatile building block in chemical research.
What is the CAS number and chemical formula?
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The CAS number is 264927-50-6, and the chemical formula is ClC6H2(SO2Cl)(F)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 98% assay. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 2-Chloro-5-chlorosulfonyl-4-fluorobenzoic acid be handled?
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This compound is classified as a Danger (GHS05) substance that causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling and emergency procedures.
How is this chemical packed and shipped?
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This chemical is packed and shipped in accordance with UN 3261, Class 8, Packing Group II regulations for hazardous materials. TSS exports globally, adhering to all relevant international shipping standards.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department directly through our website or by phone. Our team will be pleased to assist you with your specific requirements.
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