Chloroquine diphosphate salt
Chloroquine diphosphate salt (CAS: 50-63-5), with the empirical formula C18H26ClN3 · 2H3PO4 and a molecular weight of 515.86 g/mol, is a potent DNA intercalator. It is also recognised for its ability to enhance cellular transfection efficiency. This compound serves as a valuable reagent in various biological research applications, particularly in studies involving cell biology and drug transport mechanisms. Tech Serve Solutions supplies this chemical in a high-purity grade for research and development purposes.
- IUPAC
- N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
DNA Intercalation
Chloroquine diphosphate salt functions as a DNA intercalator, a property exploited in molecular biology research to study DNA-protein interactions and DNA structure. Its ability to bind within the DNA helix makes it a tool for investigating DNA replication and transcription processes.
Transfection Enhancement
This compound is utilised to increase the efficiency of gene transfection into cells. By modifying the cellular environment or the endosomal pathway, chloroquine diphosphate salt can improve the uptake and expression of exogenous DNA or RNA.
Cell Biology Research
As a bioactive small molecule, it finds application in cell biology, particularly in research related to autophagy and cell signaling. Its known effects on cellular processes make it a useful probe for understanding complex biological pathways.
| Molecular weight | 515.86 |
|---|---|
| Empirical formula | C18H26ClN3 · 2H3PO4 |
| Assay | ≥98% |
| Form | solid |
| Impurities tested | ≤2% water |
| Application | DNA intercalator. Also used to increase transfection efficiency. |
| Melting point | 200 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ABCC1(4363) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloroquine diphosphate salt used for?
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Chloroquine diphosphate salt is used as a DNA intercalator and to enhance transfection efficiency in research applications.
What is the CAS number and chemical formula for Chloroquine diphosphate salt?
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The CAS number is 50-63-5 and the chemical formula is C18H26ClN3 · 2H3PO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloroquine diphosphate salt with an assay of ≥98% and ≤2% water. This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
How should Chloroquine diphosphate salt be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid dust formation and inhalation. This compound is classified as harmful if swallowed (H302).
How is this chemical packed and shipped?
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Chloroquine diphosphate salt is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Chloroquine diphosphate salt?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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