2-Ethoxy-4-fluorophenylboronic acid
2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is an organoboron compound with the molecular formula FC<sub>6</sub>H<sub>3</sub>(OCH<sub>2</sub>CH<sub>3</sub>)B(OH)<sub>2</sub> and a molecular weight of 183.97 g/mol. This aryl boronic acid derivative serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is suitable for research and development purposes in various chemical disciplines.
Organic Synthesis Intermediate
Utilised as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. Its structure allows for the introduction of the 2-ethoxy-4-fluorophenyl moiety into complex molecules.
Pharmaceutical Research
Employed in the synthesis of novel pharmaceutical candidates and active pharmaceutical ingredients (APIs). The fluorophenyl and ethoxy groups can influence pharmacokinetic properties of drug molecules.
Materials Science
Can be incorporated into the design and synthesis of advanced materials, potentially for applications in electronics or optoelectronics, leveraging the electronic properties of the substituted aryl ring.
| Molecular weight | 183.97 |
|---|---|
| Linear formula | FC6H3(OCH2CH3)B(OH)2 |
| Melting point | 136-141 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Ethoxy-4-fluorophenylboronic acid used for?
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2-Ethoxy-4-fluorophenylboronic acid is primarily used as an intermediate in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research and materials science.
What are the CAS number and chemical formula for 2-Ethoxy-4-fluorophenylboronic acid?
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The CAS number is 480438-58-2, and the chemical formula is FC<sub>6</sub>H<sub>3</sub>(OCH<sub>2</sub>CH<sub>3</sub>)B(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Ethoxy-4-fluorophenylboronic acid for research and development. The specific assay and purity are detailed in the product specifications; it is not supplied as USP, BP, or EP grade.
How should 2-Ethoxy-4-fluorophenylboronic acid be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a type N95 (US) or P1 (EN143) respirator filter if exposure limits may be exceeded. Avoid contact with skin and eyes. Refer to the Safety Data Sheet for comprehensive handling information.
Is 2-Ethoxy-4-fluorophenylboronic acid a controlled substance?
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Based on the provided data, 2-Ethoxy-4-fluorophenylboronic acid is not listed as a controlled substance.
How is 2-Ethoxy-4-fluorophenylboronic acid packed and shipped?
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2-Ethoxy-4-fluorophenylboronic acid is carefully packed according to industry standards for chemical reagents and is available for global export by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or a sample of 2-Ethoxy-4-fluorophenylboronic acid, please contact our sales team through the website or by phone, referencing the product CAS number 480438-58-2.
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