2-Ethoxy-5-methylphenylboronic acid
2-Ethoxy-5-methylphenylboronic acid (CAS: 123291-97-4) is an organoboron compound with the formula C6H3CH3OCH2CH3B(OH)2 and a molecular weight of 180.01 g/mol. This aryl boronic acid derivative is primarily utilised as a versatile building block in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling. Its substituted phenyl ring offers specific reactivity for the construction of complex organic molecules.

Suzuki-Miyaura Coupling Reagent
2-Ethoxy-5-methylphenylboronic acid serves as a key coupling partner in Suzuki-Miyaura reactions. This allows for the facile formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Organic Synthesis Building Block
This compound is a valuable intermediate in the multi-step synthesis of various organic molecules. Its boronic acid functionality can be readily transformed into other functional groups or used to introduce the substituted phenyl moiety.
Pharmaceutical Intermediate Development
The structural motif present in 2-Ethoxy-5-methylphenylboronic acid is relevant in the design and synthesis of potential pharmaceutical agents. It can be incorporated into drug discovery programmes for creating novel therapeutic candidates.
| Molecular weight | 180.01 |
|---|---|
| Linear formula | C6H3CH3OCH2CH3B(OH)2 |
| Melting point | 89-94 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Ethoxy-5-methylphenylboronic acid used for?
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2-Ethoxy-5-methylphenylboronic acid is primarily used as a versatile building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds and construct complex organic molecules.
What is the CAS number and chemical formula for 2-Ethoxy-5-methylphenylboronic acid?
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The CAS number is 123291-97-4 and the chemical formula is C6H3CH3OCH2CH3B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2-Ethoxy-5-methylphenylboronic acid?
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Tech Serve Solutions supplies 2-Ethoxy-5-methylphenylboronic acid typically at a research or technical grade. We do not represent this product as USP, BP, or EP grade. Please refer to the product's Certificate of Analysis for specific purity details.
What are the safety considerations when handling 2-Ethoxy-5-methylphenylboronic acid?
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Handling 2-Ethoxy-5-methylphenylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet (SDS) for full hazard information.
How is 2-Ethoxy-5-methylphenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals according to stringent international regulations for safe transport. We are experienced exporters of fine chemicals globally, ensuring compliance with all relevant shipping requirements.
How can I request a sample or a quote for 2-Ethoxy-5-methylphenylboronic acid?
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To request a sample or a quotation for 2-Ethoxy-5-methylphenylboronic acid, please contact our sales department through the website or by phone. Provide the product name and CAS number for prompt service.
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