Chloro-IB-MECA
Chloro-IB-MECA (CAS 163042-96-4), with the empirical formula C18H18ClIN6O4 and a molecular weight of 544.73, is a white solid chemical. It functions as a selective agonist for adenosine receptors, particularly A3. This compound is a valuable tool in biochemical research, aiding investigations into cellular signaling pathways, neuroscience, and neurotransmission. Its properties make it useful for studying purinergic signaling systems.
- IUPAC
- 2-Chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide,Cl-IB-MECA
- Synonyms
- 2-Chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide
Adenosine Receptor Research
Chloro-IB-MECA serves as a selective agonist for the A3 adenosine receptor subtype. It is utilized in research to probe the physiological roles and therapeutic potential associated with A3 receptor activation in various biological systems.
Neuroscience and Cell Signaling Studies
This compound is employed in studies investigating neurotransmission and cellular signaling cascades. Its ability to modulate adenosine receptor activity provides insights into complex neuronal communication and cell responses.
Biochemical Assays
As a high-purity (≥98% HPLC) bioactive small molecule, Chloro-IB-MECA is suitable for use in various biochemical assays requiring specific receptor activation or modulation.
| Molecular weight | 544.73 |
|---|---|
| Empirical formula | C18H18ClIN6O4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mL |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro-IB-MECA used for?
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Chloro-IB-MECA is primarily used as a selective agonist for the A3 adenosine receptor in biochemical and neuroscience research, aiding studies on cellular signaling and neurotransmission.
What is the CAS number and chemical formula for Chloro-IB-MECA?
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The CAS number for Chloro-IB-MECA is 163042-96-4, and its empirical formula is C18H18ClIN6O4.
What grade and purity does Tech Serve Solutions supply for Chloro-IB-MECA?
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Tech Serve Solutions supplies Chloro-IB-MECA with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Chloro-IB-MECA be handled safely?
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Chloro-IB-MECA is classified as a Warning substance (H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes.
How is Chloro-IB-MECA packed and shipped?
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Chloro-IB-MECA is typically supplied as a white solid. Shipments adhere to all relevant national and international regulations for chemical transport.
How can I request a sample or quote for Chloro-IB-MECA?
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To request a sample or a quotation for Chloro-IB-MECA, please contact our sales department through the website or by phone, providing your specific requirements.
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