Chlormethiazole hydrochloride
Chlormethiazole hydrochloride (CAS 6001-74-7) is an off-white powder with a molecular weight of 198.11 g/mol. This compound, with the empirical formula C6H8ClNS · HCl, is known for its activity as a GABAergic agent. It functions as a modulator of GABA and glycine receptors, playing a role in neurotransmission. Chlormethiazole hydrochloride is recognized for its applications in research settings, particularly within neuroscience and cell biology, for studying neurological pathways.
- IUPAC
- 4-methyl-5-(β-chloroethyl)thiazole hydrochloride,5-(2-Chloroethyl)-4-methylthiazole hydrochloride,Clomethiazole hydrochloride,Somnevrin hydrochloride
- Synonyms
- 4-methyl-5-(β-chloroethyl)thiazole hydrochloride5-(2-Chloroethyl)-4-methylthiazole hydrochlorideClomethiazole hydrochlorideSomnevrin hydrochloride

Neuroscience Research
Utilised in the study of neurotransmission and the function of GABA and glycine receptors. Its properties make it valuable for investigating neurological pathways and cell signaling.
Cell Biology Investigations
Serves as a bioactive small molecule for research into cellular mechanisms, particularly those involving ion channels and receptor modulation.
Pharmacological Studies
As an approved therapeutic candidate and a known modulator of ligand-gated ion channels, it is employed in preclinical research to understand its pharmacological profile.
| Molecular weight | 198.11 |
|---|---|
| Empirical formula | C6H8ClNS · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white |
| Solubility | H2O: soluble >10 mg/mL |


Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | Store desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlormethiazole hydrochloride used for?
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Chlormethiazole hydrochloride is used in research settings, particularly in neuroscience and cell biology, for its activity as a GABAergic agent and modulator of GABA and glycine receptors.
What is the CAS number and chemical formula for Chlormethiazole hydrochloride?
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The CAS number is 6001-74-7, and its empirical formula is C6H8ClNS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlormethiazole hydrochloride with a purity of ≥98% (HPLC). This is a research grade chemical and is not represented as USP, BP, or EP grade.
How should Chlormethiazole hydrochloride be handled safely?
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Chlormethiazole hydrochloride is a Danger hazard. Handling requires a dust mask type N95 (US), eyeshields, faceshields, and gloves. It is harmful if swallowed, may cause an allergic skin reaction, and causes serious eye damage.
Is Chlormethiazole hydrochloride a controlled substance?
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The provided data does not indicate Chlormethiazole hydrochloride is a controlled substance. However, users should verify local regulations.
How is Chlormethiazole hydrochloride packed and shipped?
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Chlormethiazole hydrochloride is stored desiccated. Tech Serve Solutions exports fine chemicals globally, adhering to relevant shipping and handling regulations.
How can I request a sample or quote for Chlormethiazole hydrochloride?
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To request a sample or quote, please contact Tech Serve Solutions through our website or designated sales channels, providing product details and your requirements.
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