Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II), CAS 1028206-56-5, possesses a molecular weight of 738.76 g/mol. This palladium(II) complex serves as a sophisticated catalyst, primarily in advanced organic synthesis. It is particularly valued for its efficacy in facilitating various cross-coupling reactions, making it an essential reagent for chemists engaged in the development of complex molecules within pharmaceutical research and materials science.
- IUPAC
- (2-Dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) chloride,(XPhos) palladium(II) phenethylamine chloride,XPhos Palladacycle,XPhos precatalyst
- Synonyms
- 1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II),1028206-56-5, C41H59ClNPPd,(XPhos) palladium(II) phenethylamine chloride,XPhos Palladacycle,XPhos precatalyst
![Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) (C41H59ClNPPd) — chemical structure, CAS 1028206-56-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1028206-56-5.png&w=3840&q=75)
Palladium-Catalyzed Cross-Coupling Reactions
This palladium complex is a highly effective catalyst for a range of cross-coupling reactions, including amination, boration of aryl chlorides, and arylation of oxazoles. It enables efficient formation of new carbon-carbon and carbon-heteroatom bonds.
C-N Bond Formation
It is instrumental in C-N bond-forming reactions. Its application in packed-bed microreactors has been demonstrated, offering potential for continuous flow synthesis and improved reaction control.
Buchwald Ligands and Complexes
As a member of the Buchwald 1st Generation Palladacycles, this compound embodies advanced catalytic design. It is a valuable tool for chemists working with homogeneous palladium catalysis.
| Molecular weight | 738.76 |
|---|---|
| Empirical formula | C41H59ClNPPd |
| Application | Application Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst used for:• Amination / cyclization reactions1• C-N bond-forming reactions via packed-bed microreactors2• Boration of aryl chlorides3• Arylation of oxazole4• Cross-coupling reactions5,6 |
| Melting point | 205-210 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-52/53 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II) used for?
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This compound is primarily used as a catalyst in palladium-catalyzed cross-coupling reactions, including amination, cyclization, C-N bond formation, boration of aryl chlorides, and arylation of oxazoles.
What are the CAS number and formula for this chemical?
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The CAS number is 1028206-56-5, and the empirical formula is C41H59ClNPPd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research or technical grade reagent. We do not represent it as USP, BP, EP, or any pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is also harmful to aquatic life with long-lasting effects (H412). Use a dust mask (type N95), wear eyeshields and gloves. Avoid breathing dust, and ensure good ventilation. Avoid release to the environment. See full safety data for specific precautions.
Can Tech Serve Solutions pack, ship, and export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can fulfil packing, shipping, and export requirements for this product.
How do I request a sample or quote?
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To request a sample or a quotation, please contact our sales team via the website or your usual account manager, providing the product name and CAS number.
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