Berberine chloride form

CAS 633-65-8C20H18ClNO4Biochemicals & Reagents

Berberine chloride form (CAS 633-65-8) is a bright yellow quaternary ammonium salt of the protoberberine alkaloid group. With a molecular weight of 371.81 g/mol and empirical formula C20H18ClNO4, this compound is recognised for its biological activity. Primarily, it serves as a fluorescent stain for identifying heparin in mast cells, aiding in histological and biological research. Its applications extend into areas such as cancer research and cell biology due to its inherent bioactive properties.

IUPAC: Natural Yellow 18

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Berberine chloride form (C20H18ClNO4) — chemical structure, CAS 633-65-8; Life Science, fine chemical supplied by Tech Serve Solutions

AlkaloidAnti-Proliferative AgentsAntitumor AgentsBioactive Small MoleculesBiochemicals and ReagentsCancer ResearchCell BiologyDrug Efflux PumpsDrug Transport Compounds

01 /Applications

Histological Staining

Berberine chloride form functions as a specific fluorescent stain for the visualisation of heparin within mast cells. This application is crucial in microscopic studies for identifying and analysing mast cell distribution and heparin content in biological tissues.

Biological Research

As a bioactive small molecule, this compound is employed in various biological research settings. Its properties make it valuable for investigating cellular processes, including cell signalling and understanding the mechanisms behind anti-proliferative and antitumor activities.

Drug Efflux Pump Studies

This alkaloid is also utilised in research focused on drug transport and efflux pumps. It serves as a tool for studying membrane protein biology and modulators of multidrug resistance (MDR) and ATP-binding cassette (ABC) transporters.

02 /Properties

Molecular weight	371.81
Empirical formula	C20H18ClNO4
Solubility	methanol: soluble
Application	Fluorescent stain for heparin in mast cells

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

633-65-8

MDL number

MFCD00011939

PubChem substance

24891691

Beilstein registry

3836585

05 /Additional specifications

Colour Index Number	75160

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Berberine chloride form primarily used for?

Berberine chloride form is primarily used as a fluorescent stain for heparin in mast cells, and also finds application in cancer research, cell biology, and studies related to drug transport mechanisms.

What are the CAS number and formula for Berberine chloride form?

The CAS number for Berberine chloride form is 633-65-8, and its empirical formula is C20H18ClNO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Berberine chloride form as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia standard unless explicitly stated in the product specifications.

What safety precautions should be taken when handling Berberine chloride form?

When handling Berberine chloride form (WGK Germany: 2), it is essential to wear eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended for respiratory protection.