2-(Benzyloxy)phenylboronic acid
2-(Benzyloxy)phenylboronic acid (CAS 190661-29-1) is an organoboron compound with the formula C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>OC<sub>6</sub>H<sub>4</sub>B(OH)<sub>2</sub> and a molecular weight of 228.05 g/mol. This aryl boronic acid derivative serves as a valuable reactant in various synthetic organic chemistry applications, notably in palladium-catalysed cross-coupling reactions and other sophisticated transformations.
- IUPAC
- 2-(Phenylmethoxy)benzeneboronic acid,2-(Phenylmethyl)oxyphenylboronic acid
- Synonyms
- 2-(Phenylmethoxy)benzeneboronic acid2-(Phenylmethyl)oxyphenylboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
2-(Benzyloxy)phenylboronic acid is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. This is a fundamental transformation in the synthesis of complex organic molecules.
Palladium-Catalyzed Selective Hydroxylation
It functions as a reactant in palladium complex-catalyzed selective hydroxylation processes. This application is crucial for introducing hydroxyl groups regioselectively into organic structures.
Oxidative Heck Reactions
The compound participates in palladium(II)-catalyzed oxidative Heck reactions. These reactions are important for constructing substituted alkenes and other valuable unsaturated organic compounds.
Electrophilic Fluorination
2-(Benzyloxy)phenylboronic acid is employed in metal-free electrophilic fluorination methods, facilitating the introduction of fluorine atoms into organic molecules under mild conditions.
| Molecular weight | 228.05 |
|---|---|
| Linear formula | C6H5CH2OC6H4B(OH)2 |
| Application | Reactant for:• Palladium complex-catalyzed selective hydroxylation1• Palladium(II)-catalyzed oxidative Heck reactions2• Metal-free electrophilic fluorination3• Suzuki-Miyaura cross-coupling reactions4 |
| Melting point | 105-110 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Benzyloxy)phenylboronic acid used for?
+
2-(Benzyloxy)phenylboronic acid is used as a reactant in various organic synthesis applications, including palladium-catalyzed selective hydroxylation, palladium(II)-catalyzed oxidative Heck reactions, metal-free electrophilic fluorination, and Suzuki-Miyaura cross-coupling reactions.
What is the CAS number and formula for 2-(Benzyloxy)phenylboronic acid?
+
The CAS number for 2-(Benzyloxy)phenylboronic acid is 190661-29-1, and its molecular formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>OC<sub>6</sub>H<sub>4</sub>B(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply for 2-(Benzyloxy)phenylboronic acid?
+
Tech Serve Solutions supplies 2-(Benzyloxy)phenylboronic acid as a research-grade chemical. TSS does not represent this product as meeting USP, BP, EP, or any other pharmacopoeial standards.
How is 2-(Benzyloxy)phenylboronic acid supplied and exported by TSS?
+
2-(Benzyloxy)phenylboronic acid is carefully packed and handled by Tech Serve Solutions for both domestic supply and global export. Our experienced logistics team ensures compliance with all relevant shipping regulations.
What are the safety and handling considerations for 2-(Benzyloxy)phenylboronic acid?
+
When handling 2-(Benzyloxy)phenylboronic acid, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet for comprehensive handling information.
How can I request a quote or sample of 2-(Benzyloxy)phenylboronic acid?
+
To request a quote or a sample of 2-(Benzyloxy)phenylboronic acid, please contact the Tech Serve Solutions sales team through our website or by phone. Our representatives will be pleased to assist you with your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis