Calphostin C from Cladosporium cladosporioides
Calphostin C (CAS: 121263-19-2), with the molecular formula C44H38O14 and a molecular weight of 790.76 g/mol, is a potent inhibitor derived from the fungus Cladosporium cladosporioides. This complex organic molecule exhibits significant biological activity, particularly as an inhibitor of protein kinase C (PKC). Its well-defined chemical structure and inhibitory properties make it a valuable tool in biochemical research for studying cellular signaling pathways.
- IUPAC
- UCN-1028c
Protein Kinase C (PKC) Inhibition
Calphostin C serves as a selective inhibitor of Protein Kinase C (PKC) isoforms. It is extensively used in research to elucidate the role of PKC in various cellular processes, including cell proliferation, differentiation, and apoptosis.
Cellular Signaling Research
This compound is a critical reagent for investigating signal transduction pathways. Its ability to modulate PKC activity allows researchers to study downstream effects in cell signaling, making it valuable in neuroscience and cell biology research.
Biochemical Assays
Calphostin C is employed in biochemical assays to understand enzyme kinetics and inhibitory mechanisms of protein kinases. Its defined purity ensures reliable and reproducible experimental results.
| Molecular weight | 790.76 |
|---|---|
| Empirical formula | C44H38O14 |
| Assay | ≥90% (HPLC) |
| Form | powder |
| Colour | red to brown |
| Solubility | DMF: soluble1 mg/mLDMSO: soluble1 mg/mLethanol: soluble1 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Calphostin C used for?
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Calphostin C is primarily used in research as a selective inhibitor of Protein Kinase C (PKC) and for studying cellular signaling pathways, including those relevant to cell biology and neuroscience.
What are the CAS number and formula for Calphostin C?
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The CAS number for Calphostin C is 121263-19-2, and its molecular formula is C44H38O14.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Calphostin C with an assay of ≥90% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Calphostin C be handled and stored?
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When handling Calphostin C, use personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store the compound at −20°C. Observe all safety precautions indicated by WGK Germany 3 classification.
How is Calphostin C packed, shipped, and exported?
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Calphostin C is carefully packaged to maintain its integrity during transit and is available for global export. Specific packaging details are provided upon order confirmation.
How can I request a quote or sample for Calphostin C?
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To request a quote or a sample of Calphostin C, please use the contact form on our website or email our sales department. Our team will promptly assist you with your inquiry.
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