Boc-OSu
Boc-OSu (CAS: 13139-12-3; Formula: C9H13NO5; Molar Mass: 215.20 g/mol) is a valuable reagent in organic synthesis, primarily employed for the efficient protection of primary and secondary amines. It serves as a key building block in peptide chemistry and the synthesis of complex organic molecules. Its reactivity allows for the introduction of the tert-butoxycarbonyl (Boc) protecting group under mild conditions, facilitating downstream chemical transformations.
- IUPAC
- N-(tert-Butoxycarbonyloxy)succinimide,tert-Butyl N-succinimidyl carbonate
- Synonyms
- N-(tert-Butoxycarbonyloxy)succinimidetert-Butyl N-succinimidyl carbonate
Amine Protection in Peptide Synthesis
Boc-OSu is widely utilized to introduce the Boc protecting group onto the amine functionalities of amino acids. This protection is crucial for preventing unwanted side reactions during solid-phase or solution-phase peptide synthesis, ensuring the correct assembly of peptide chains.
Synthesis of Organic Intermediates
This reagent facilitates the selective functionalisation of molecules containing amine groups. It is instrumental in the preparation of various pharmaceutical intermediates and complex organic compounds where controlled amine derivatisation is required.
Chemical Biology Applications
In chemical biology research, Boc-OSu can be employed to modify biomolecules containing amine groups, enabling the study of their function or the development of new chemical probes.
| Molecular weight | 215.20 |
|---|---|
| Empirical formula | C9H13NO5 |
| Assay | ≥98.0% (CHN) |
| Storage temperature | −20°C |
| Melting point | ~95 °C (dec.) |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-OSu used for?
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Boc-OSu (tert-Butyl N-succinimidyl carbonate) is primarily used for the efficient protection of amine groups in organic synthesis, particularly in peptide chemistry and the synthesis of complex organic molecules.
What is the CAS number and formula for Boc-OSu?
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The CAS number for Boc-OSu is 13139-12-3, and its empirical formula is C9H13NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-OSu with an assay of ≥98.0% (CHN). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should Boc-OSu be handled safely?
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Boc-OSu is classified with H302 (Harmful if swallowed) and H317 (May cause an allergic skin reaction). Handle with appropriate personal protective equipment including a dust mask (N95 US recommended), eyeshields, face shields, and gloves. Store at -20°C.
How is Boc-OSu shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Boc-OSu is carefully packaged and prepared for domestic and international shipment, adhering to all relevant shipping regulations.
How can I request a sample or quote for Boc-OSu?
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To request a sample or a quote for Boc-OSu, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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