Boc-Nva-OH
Boc-Nva-OH (CAS: 53308-95-5), also known as N-tert-butoxycarbonyl-L-norvaline, is a protected amino acid derivative with the molecular formula C10H19NO4. It serves as a crucial building block in peptide synthesis and in the development of unnatural amino acid derivatives. Its protected nature allows for controlled incorporation into peptide chains, facilitating research in chemical biology and organic synthesis.
- IUPAC
- Boc-L-norvaline
- Synonyms
- N-tert-butoxycarbonyl-L-norvalineN-(tert-Butoxycarbonyl)-L-norvaline
Peptide Synthesis
Boc-Nva-OH is utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) protecting group can be selectively removed under acidic conditions, enabling controlled chain elongation.
Chemical Biology Research
This compound finds application in chemical biology for creating modified peptides or peptidomimetics. Its incorporation can help researchers study protein function, enzyme mechanisms, or develop novel biologically active molecules.
Unnatural Amino Acid Derivatives
As a derivative of norvaline, Boc-Nva-OH is employed in the synthesis of unnatural amino acids. These modified building blocks are valuable for introducing unique structural or functional properties into peptides and proteins.
Organic Synthesis Intermediate
Beyond peptide chemistry, Boc-Nva-OH can function as an intermediate in various organic synthesis pathways. Its functional groups allow for diverse chemical transformations, contributing to the creation of complex organic molecules.
| Molecular weight | 217.26 |
|---|---|
| Empirical formula | C10H19NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Nva-OH used for?
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Boc-Nva-OH is primarily used as a protected amino acid building block in peptide synthesis and for creating unnatural amino acid derivatives in chemical biology and organic synthesis research.
What are the CAS number and chemical formula for Boc-Nva-OH?
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The CAS number for Boc-Nva-OH is 53308-95-5, and its empirical formula is C10H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Nva-OH with a purity of ≥98.0% (TLC), identified as Boc-L-norvaline. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Boc-Nva-OH be handled safely?
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When handling Boc-Nva-OH, it is recommended to wear eyeshields and gloves. The compound is classified under WGK Germany 3, indicating a potential hazard to water.
Is Boc-Nva-OH a controlled substance?
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The provided data does not indicate that Boc-Nva-OH is a controlled substance.
How is Boc-Nva-OH packed and shipped?
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Boc-Nva-OH is carefully packed for safe transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Boc-Nva-OH?
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To request a sample or obtain a quote for Boc-Nva-OH, please contact our sales team through the TSS website.
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