Boc-Nle-OH
Boc-Nle-OH (CAS: 6404-28-0), also known as N-tert-butoxycarbonyl-L-norleucine, is a protected amino acid derivative with the molecular formula C11H21NO4 and a molecular weight of 231.29 g/mol. It is crucial in peptide synthesis, serving as a building block for complex peptide chains. This compound finds applications in chemical biology and general chemical synthesis, facilitating the creation of novel biomolecules and research compounds.
- IUPAC
- (S)-2-(Boc-amino)caproic acid,(S)-2-(Boc-amino)hexanoic acid,Boc-L-norleucine
- Synonyms
- N-tert-butoxycarbonyl-L-norleucineBoc-L-Norleucine(S)-2-(Boc-amino)caproic acid(S)-2-(Boc-amino)hexanoic acid

Peptide Synthesis
Boc-Nle-OH is a valuable protected amino acid used in solid-phase and solution-phase peptide synthesis. Its Boc protecting group allows for controlled sequential addition of amino acids, enabling the construction of peptides with specific sequences.
Chemical Biology Research
As an unnatural amino acid derivative, Boc-Nle-OH is employed in chemical biology to create modified peptides and proteins. This allows researchers to study protein structure, function, and interactions, or to develop novel biochemical tools.
Organic Synthesis
This compound serves as a versatile chiral building block in organic synthesis. It can be incorporated into a variety of molecules requiring a protected norleucine moiety or a related chiral structure.
| Molecular weight | 231.29 |
|---|---|
| Empirical formula | C11H21NO4 |
| Assay | ≥99.0% (TLC) |
| Optical activity | [α]20/D −8±1°, c = 1% in methanol |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Nle-OH used for?
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Boc-Nle-OH is primarily used as a protected amino acid building block in peptide synthesis and in chemical biology research for creating modified peptides and proteins, as well as in general organic synthesis.
What is the CAS number and chemical formula for Boc-Nle-OH?
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The CAS number for Boc-Nle-OH is 6404-28-0, and its chemical formula is C11H21NO4.
What grade and purity does Tech Serve Solutions supply for Boc-Nle-OH?
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Tech Serve Solutions supplies Boc-Nle-OH with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Boc-Nle-OH?
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Handling Boc-Nle-OH requires appropriate personal protective equipment, including eyeshields and gloves, to prevent contact. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is Boc-Nle-OH packed, shipped, and exported?
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Boc-Nle-OH is carefully packed to ensure stability during transit. As a global supplier, Tech Serve Solutions professionally handles the export of this chemical, adhering to all relevant regulations.
How can I request a sample or quote for Boc-Nle-OH?
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To request a sample or obtain a quote for Boc-Nle-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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