Boc-Orn(2-Cl-Z)-OH
Nα-Boc-Nδ-(2-chloro-Z)-L-ornithine (CAS: 118554-00-0) is a protected ornithine derivative with the molecular formula C18H25ClN2O6 and a molecular weight of 400.85 g/mol. This compound serves as a valuable building block in peptide synthesis and chemical biology research. Its specific protecting groups facilitate controlled chain elongation in the creation of complex peptides and peptidomimetics.
- IUPAC
- Nα-Boc-Nδ-(2-chloro-Z)-L-ornithine
- Synonyms
- Nα-Boc-Nδ-(2-chloro-Z)-L-ornithine
Peptide Synthesis
Utilised as a protected amino acid derivative in solid-phase or solution-phase peptide synthesis to incorporate modified ornithine residues into peptide chains. The Boc and 2-chloro-Z protecting groups enable orthogonal deprotection strategies.
Chemical Biology
Serves as a precursor for synthesising modified peptides or probes designed to investigate biological pathways or protein interactions. Its unnatural structure can confer specific properties or functionalities.
Medicinal Chemistry
A key intermediate in the development of novel therapeutic agents. The incorporation of unnatural amino acids like this protected ornithine can modulate pharmacokinetic and pharmacodynamic properties of drug candidates.
Organic Synthesis
Employed as a chiral building block in complex organic syntheses requiring specific stereochemistry and functional group manipulation, particularly within the field of natural product synthesis.
| Molecular weight | 400.85 |
|---|---|
| Empirical formula | C18H25ClN2O6 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −2.8±0.5°, c = 1% in acetic acid |
| Melting point | 114-118 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Orn(2-Cl-Z)-OH used for?
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Boc-Orn(2-Cl-Z)-OH is primarily used as a protected amino acid building block in peptide synthesis and in chemical biology for creating modified peptides and probes. It also finds application in medicinal chemistry and general organic synthesis.
What are the CAS number and formula for Boc-Orn(2-Cl-Z)-OH?
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The CAS number is 118554-00-0, and the empirical formula is C18H25ClN2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Orn(2-Cl-Z)-OH with an assay of ≥98.0% (TLC). This is a research-grade chemical and is not supplied as USP, BP, EP, or for pharmaceutical, nutraceutical, or food applications.
How should Boc-Orn(2-Cl-Z)-OH be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. The compound is classified under WGK 3 in Germany, indicating a high hazard to water.
Is Boc-Orn(2-Cl-Z)-OH a controlled substance?
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The provided data does not indicate that Boc-Orn(2-Cl-Z)-OH is a controlled substance. However, users should always verify local regulations.
How is this product packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Products are typically packed securely in appropriate containers to ensure integrity during transit. Please contact us for specific export and shipping details.
How can I request a quote or sample?
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To request a quote or a sample of Boc-Orn(2-Cl-Z)-OH, please navigate to the product page and utilise the 'Request a Quote' or 'Sample Request' buttons, or contact our sales team directly.
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