Boc-Orn-OH
Nα-tert-Butoxycarbonyl-L-ornithine (CAS 21887-64-9) is a derivative of the amino acid ornithine, featuring a tert-butoxycarbonyl (Boc) protecting group on its alpha-amino nitrogen. With the molecular formula C10H20N2O4 and a molecular weight of 232.28 g/mol, this compound serves as a crucial building block in peptide synthesis and chemical biology research. Its defined structure and reactivity make it valuable for constructing peptides with unnatural amino acid residues.
- IUPAC
- Nα-tert-Butoxycarbonyl-L-ornithine,Nα-Boc-L-ornithine,N2-Boc-L-ornithine
- Synonyms
- Nα-tert-Butoxycarbonyl-L-ornithineNα-Boc-L-ornithineN2-Boc-L-ornithine
Peptide Synthesis
Nα-Boc-L-ornithine is widely employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc group facilitates controlled coupling reactions, enabling the sequential addition of amino acids to form peptide chains.
Chemical Biology
This ornithine derivative is utilized in chemical biology to introduce modified amino acid functionalities into peptides or proteins. These modifications can be used to study biological pathways, develop diagnostic tools, or create novel biomaterials.
Organic Synthesis Intermediate
As an unnatural amino acid derivative, Nα-Boc-L-ornithine acts as a versatile intermediate in complex organic synthesis. It allows for the preparation of specialised molecules containing the ornithine side chain with protected amine functionality.
| Molecular weight | 232.28 |
|---|---|
| Empirical formula | C10H20N2O4 |
| Assay | ≥98% (TLC) |
| Optical activity | [α]/D +24.0±2.0°, c = 1 in methanol |
Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-L-ornithine used for?
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Nα-Boc-L-ornithine is primarily used as a protected amino acid building block in peptide synthesis and in various applications within chemical biology and organic synthesis.
What is the CAS number and formula for Nα-Boc-L-ornithine?
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The CAS number is 21887-64-9, and the empirical formula is C10H20N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Boc-L-ornithine with an assay of ≥98% (TLC). This product is supplied for research and development purposes and is not guaranteed to be USP, BP, EP, or any other pharmacopoeia grade.
How should Nα-Boc-L-ornithine be handled?
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Nα-Boc-L-ornithine is classified as a warning substance, indicated by GHS07, and carries the hazard statement H317: May cause an allergic skin reaction. Handle with appropriate personal protective equipment, including gloves and protective clothing, to avoid skin contact. Ensure adequate ventilation. Consult the Safety Data Sheet for detailed handling information.
How is Nα-Boc-L-ornithine packed and shipped?
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Nα-Boc-L-ornithine is carefully packed to ensure product integrity during transit and is exported globally by Tech Serve Solutions in compliance with all relevant regulations.
How can I request a quote or sample?
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To request a quote or a sample of Nα-Boc-L-ornithine, please contact our sales team through the website or by email, providing your specific requirements and shipping details.
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