Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)
Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) (CAS 887919-35-9; C32H56Cl2N2P2Pd; molar mass 708.07 g/mol) is an air-stable homogeneous palladium(II) pre-catalyst bearing two electron-rich AmPhos (A-taPhos) phosphine ligands. Widely known as (A-taPhos)2PdCl2 or Pd(AmPhos)2Cl2, it is a highly active catalyst for Suzuki-Miyaura cross-coupling of aryl halides, including challenging 5- and 6-membered heteroaryl chlorides. Tech Serve Solutions supplies and exports it as a research-grade reagent for synthetic and process chemistry.
- IUPAC
- (A-taPhos)2PdCl2,Pd(amphos)Cl2
- Synonyms
- Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)(A-taPhos)2PdCl2Pd(AmPhos)2Cl2Pd(amphos)Cl2Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)palladium(II) chlorideBis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(II) dichlorideCAS 887919-35-9
Suzuki-Miyaura cross-coupling
Serves as a highly active, air-stable catalyst for Suzuki-Miyaura coupling of aryl and heteroaryl halides with boronic acids and esters. It is effective even with demanding 5- and 6-membered heteroaryl chlorides.
Biaryl and heterobiaryl bond formation
Used to construct carbon-carbon bonds between aromatic and heteroaromatic partners. The electron-rich AmPhos ligands promote oxidative addition into less reactive aryl chloride substrates.
Pharmaceutical and agrochemical research synthesis
Applied in laboratory and process route development where palladium-catalysed cross-coupling builds key biaryl and heteroaryl motifs. Specific routes depend entirely on the customer's chemistry.
Convenient benchtop pre-catalyst
As a defined, air-stable palladium(II) complex it offers reproducible loading and straightforward handling for homogeneous catalysis, avoiding in-situ ligand and palladium mixing.
| Molecular weight | 708.07 |
|---|---|
| Empirical formula | C32H56Cl2N2P2Pd |
| Application | Higly active, air-stable catalyst for Suzuki-Miyaura cross-coupling with aryl halides including 5- and 6-membered heteroaryl chlorides.1 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) used for?
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It is used as a highly active, air-stable palladium(II) catalyst for Suzuki-Miyaura cross-coupling of aryl halides, including 5- and 6-membered heteroaryl chlorides. It is a homogeneous pre-catalyst for forming carbon-carbon bonds in synthetic and process chemistry.
What is the CAS number and molecular formula of Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)?
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The CAS number is 887919-35-9 and the empirical formula is C32H56Cl2N2P2Pd, with a molecular weight of 708.07 g/mol. The MDL number is MFCD09265123 and the PubChem Substance ID is 24885453.
What grade and purity does Tech Serve Solutions supply?
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We supply this palladium complex as a research- and reagent-grade catalyst suitable for synthetic and process chemistry. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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The material carries GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with an N95-type dust mask, eye protection and gloves, avoid dust formation, and consult the Safety Data Sheet before use. It is assigned WGK Germany 3 (water hazard).
How is Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) packed, shipped and exported?
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It is supplied in sealed, suitably labelled laboratory and bulk packs sized to order, with full documentation including a certificate of analysis and Safety Data Sheet. As a global exporter, Tech Serve Solutions arranges compliant international shipping and the required export paperwork.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 887919-35-9. We will respond with availability, lead time, specification and a formal quotation, and can arrange samples where appropriate.
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