Bis(2,2,2-trifluoroethyl) methylphosphonate
Bis(2,2,2-trifluoroethyl) methylphosphonate (CAS: 757-95-9) is a chemical compound with the linear formula (CF3CH2O)2P(O)CH3 and a molecular weight of 260.07 g/mol. This phosphonate ester finds application as a flame-retardant additive in lithium-ion electrolytes and serves as a versatile reagent in organic synthesis, particularly for olefination reactions and the synthesis of complex molecules.
- Synonyms
- 757-95-9, (CF3CH2O)2P(O)CH3
Flame Retardant for Electrolytes
Utilised as an effective flame-retardant additive in lithium-ion battery electrolytes, enhancing safety and performance.
Homogeneous Catalysis
Employed as a homogenous organic catalytic system, facilitating various chemical transformations.
Phosphorylation Reagent
Acts as a catalyst for the phosphorylation of polyfluoroalkanols, a key step in certain synthetic routes.
Synthesis of Biologically Active Molecules
Serves as a crucial reactant in the synthesis of complex organic molecules, including fluorescently labeled discodermolide and the anticancer macrolide (-)-dictyostatin, through phosphonate-based olefination.
| Molecular weight | 260.07 |
|---|---|
| Linear formula | (CF3CH2O)2P(O)CH3 |
| Assay | 98% |
| Boiling point | 183-184 °C(lit.) |
| Refractive index | n20/D 1.339(lit.) |
| Application | Flame-retardant additive for lithium-ion electrolytes1Used as homogenous organic catalytic system2 and as a catalyst for phosphorylation of polyfluoroalkanols3Reactant for: • Synthesis of fluorescently labeled discodermolide for studying its binding to tubulin4• Cross metathesis / phosphonate-based intramolecular olefination5• Olefination for the synthesis of the anticancer microtubule-stabilizing macrolide, (-)-dictyostatin6 |
| Melting point | 24-28 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 80 °C / 176 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2,2,2-trifluoroethyl) methylphosphonate used for?
+
It is used as a flame-retardant additive for lithium-ion electrolytes, as a homogenous organic catalytic system, as a catalyst for phosphorylation of polyfluoroalkanols, and as a reactant for various syntheses including fluorescently labeled discodermolide and (-)-dictyostatin.
What is the CAS number and formula for Bis(2,2,2-trifluoroethyl) methylphosphonate?
+
The CAS number is 757-95-9 and the linear formula is (CF3CH2O)2P(O)CH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Bis(2,2,2-trifluoroethyl) methylphosphonate with an assay of 98%. This is a technical/research grade product and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Bis(2,2,2-trifluoroethyl) methylphosphonate be handled?
+
Bis(2,2,2-trifluoroethyl) methylphosphonate is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is Bis(2,2,2-trifluoroethyl) methylphosphonate a controlled substance?
+
The provided data does not indicate that Bis(2,2,2-trifluoroethyl) methylphosphonate is a controlled substance.
How is this product packed, shipped, and exported?
+
Tech Serve Solutions packages and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally. Specific packaging and shipping details are available upon request, adhering to international regulations for chemical transport.
How can I request a sample or quote for Bis(2,2,2-trifluoroethyl) methylphosphonate?
+
To request a sample or a quote for Bis(2,2,2-trifluoroethyl) methylphosphonate, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis