Bis(2,2,2-trichloroethyl) azodicarboxylate
Bis(2,2,2-trichloroethyl) azodicarboxylate (CAS: 38857-88-4) is an organic compound with a molecular weight of 380.82 g/mol. Its linear formula is CCl₃CH₂OCON=NCOOCH₂CCl₃. This azo compound serves as a valuable reagent in various synthetic organic chemistry applications, particularly in amination reactions and asymmetric synthesis. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Azodicarboxylic acid bis(2,2,2-trichloroethyl ester)
- Synonyms
- 38857-88-4Azodicarboxylic acid bis(2,2,2-trichloroethyl ester)CCl3CH2OCON=NCOOCH2CCl3
Asymmetric Synthesis
This reagent has been utilised in the asymmetric synthesis of substituted cycloalkyl[b]indoles, contributing to the creation of complex chiral molecules.
Amination Reagent
It functions as an effective amination reagent during the aza-ene reaction of alkenes, yielding the corresponding allyl amines.
Para-Directed Amination
Bis(2,2,2-trichloroethyl) azodicarboxylate is employed in para-directed amination of anisole derivatives substituted with C₂-alkyl groups.
Diels-Alder Cycloadditions
The compound finds application in Diels-Alder cycloadditions and in the synthesis of both acid- and base-sensitive azo compounds.
| Molecular weight | 380.82 |
|---|---|
| Linear formula | CCl3CH2OCON=NCOOCH2CCl3 |
| Assay | ≥97.0% (H-NMR) |
| Storage temperature | 2-8°C |
| Application | Bis(2,2,2-trichloroethyl) azodicarboxylate has been used:• in the asymmetric synthesis of substituted cycloalkyl[b]indoles1• as amination reagent during the aza-ene reaction of different alkenes to yield the corresponding allyl amines2• in para-directed amination of C2-alkyl substituted anisole3• in the synthesis of acid- and base-sensitive azo compounds and in Diels-Alder cycloadditions4 |
| Melting point | 109-111 °C(lit.)109-111 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2,2,2-trichloroethyl) azodicarboxylate used for?
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Bis(2,2,2-trichloroethyl) azodicarboxylate is used in asymmetric synthesis, as an amination reagent in aza-ene reactions, in para-directed amination of anisoles, and in Diels-Alder cycloadditions.
What are the CAS number and formula for Bis(2,2,2-trichloroethyl) azodicarboxylate?
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The CAS number is 38857-88-4 and the linear formula is CCl₃CH₂OCON=NCOOCH₂CCl₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(2,2,2-trichloroethyl) azodicarboxylate with an assay of ≥97.0% (H-NMR). This product is intended for research and technical use and is not supplied as USP, EP, BP, or pharmacopoeia grade.
How should Bis(2,2,2-trichloroethyl) azodicarboxylate be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust. This compound is classified with Warning signal word, and hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is Bis(2,2,2-trichloroethyl) azodicarboxylate stored and shipped?
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It should be stored at 2-8°C. Tech Serve Solutions ensures reliable global export and shipping of chemicals.
How can I request a quote or sample?
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To request a quote or sample of Bis(2,2,2-trichloroethyl) azodicarboxylate, please contact the Tech Serve Solutions sales team through our website or by phone.
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