Bis(2,2,2-trichloroethyl) phosphorochloridate
Bis(2,2,2-trichloroethyl) phosphorochloridate (CAS 17672-53-6) is a phosphorus halide compound with the linear formula (Cl 3 CCH 2 O) 2 P(O)Cl and a molecular weight of 379.22 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the preparation of phosphorylated organic molecules. Its reactivity makes it suitable for specialised chemical transformations within research and development settings.
- Synonyms
- 17672-53-6(Cl3CCH2O)2P(O)Cl

Nucleoside Phosphate Synthesis
This compound has been utilised in the synthesis of epimeric 6-deoxyhexofuranosyl nucleoside 5'-phosphates, contributing to the study of complex carbohydrate and nucleic acid chemistry.
Organic Building Block
As a phosphorus halide, it functions as a versatile building block in organic synthesis, enabling the introduction of specific phosphorus-containing functionalities into target molecules.
Chemical Synthesis Reagent
Its reactive nature allows for its use as a reagent in various chemical synthesis pathways, particularly in the field of organophosphorus chemistry.
| Molecular weight | 379.22 |
|---|---|
| Linear formula | (Cl3CCH2O)2P(O)Cl |
| Assay | 98% |
| Application | Bis(2,2,2-trichloroethyl) phosphorochloridate was used in the preparation of epimeric 6-deoxyhexofuranosyl nucleoside 5′ -phosphate1. |
| Melting point | 45-47 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(2,2,2-trichloroethyl) phosphorochloridate used for?
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Bis(2,2,2-trichloroethyl) phosphorochloridate is used as a building block in organic synthesis, notably in the preparation of epimeric 6-deoxyhexofuranosyl nucleoside 5'-phosphates.
What is the CAS number and formula for Bis(2,2,2-trichloroethyl) phosphorochloridate?
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The CAS number is 17672-53-6, and its linear formula is (Cl 3 CCH 2 O) 2 P(O)Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(2,2,2-trichloroethyl) phosphorochloridate with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Bis(2,2,2-trichloroethyl) phosphorochloridate be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection. Ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling instructions.
Is Bis(2,2,2-trichloroethyl) phosphorochloridate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Bis(2,2,2-trichloroethyl) phosphorochloridate.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team via the website or provide your requirements through the product inquiry form.
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