Tos-Pro-OH
Tos-Pro-OH (CAS: 51077-01-1) is an organic compound with the molecular formula C12H15NO4S and a molecular weight of 269.32 g/mol. This proline derivative, also known as N-p-Tosyl-L-proline, is primarily utilised in chemical synthesis and peptide chemistry. It serves as a valuable building block in organic chemistry research and development, offering specific stereochemical properties due to its L-proline origin. Available at 97% purity, Tos-Pro-OH is supplied by Tech Serve Solutions for laboratory and research applications.
- IUPAC
- (S)-N-Toluenesulfonylpyrrolidine-2-carboxylic acid,N-p-Tosyl-L-proline,N-Toluenesulfonyl-L-proline

Chemical Synthesis
Tos-Pro-OH serves as a chiral building block in the synthesis of complex organic molecules. Its protected proline structure facilitates specific reaction pathways in multi-step syntheses.
Peptide Chemistry
As a modified amino acid derivative, Tos-Pro-OH is employed in the construction of peptides and peptidomimetics. It can introduce specific structural constraints or functionalities into peptide sequences.
Chemical Biology Research
This compound can be used as a tool or intermediate in research focused on understanding biological processes at a molecular level. Its unique structure may lend itself to probing specific enzymatic or receptor interactions.
| Molecular weight | 269.32 |
|---|---|
| Empirical formula | C12H15NO4S |
| Assay | 97% |
| Melting point | 80-90 °C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tos-Pro-OH used for?
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Tos-Pro-OH is primarily used in chemical synthesis and peptide chemistry as a chiral building block and for the construction of peptides and peptidomimetics.
What are the CAS number and formula for Tos-Pro-OH?
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The CAS number for Tos-Pro-OH is 51077-01-1 and its empirical formula is C12H15NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tos-Pro-OH with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Tos-Pro-OH be handled safely?
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Tos-Pro-OH is classified under GHS06 with the signal word 'Danger' and carries hazard statement H301 (Toxic if swallowed). Handle with extreme care, wearing appropriate personal protective equipment, and avoid ingestion. Consult the Safety Data Sheet (SDS) for detailed handling instructions.
Is Tos-Pro-OH shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tos-Pro-OH, and can facilitate international shipments.
How can I request a sample or quote for Tos-Pro-OH?
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To request a sample or a quote for Tos-Pro-OH, please contact our sales department via the website or direct email, providing your specific requirements.
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