Tolylene 2,5-diisocyanate
Tolylene 2,5-diisocyanate (CAS 614-90-4) is an organic compound with the linear formula CH₃C₆H₃(NCO)₂ and a molecular weight of 174.16 g/mol. This diisocyanate is a valuable intermediate in chemical synthesis, particularly for the production of polymers and other organic materials. It possesses two reactive isocyanate groups that readily participate in addition reactions, making it a key building block in various industrial and research applications.
- Synonyms
- CH3C6H3(NCO)2

Polymer Synthesis
Tolylene 2,5-diisocyanate serves as a monomer or cross-linking agent in the synthesis of polyurethanes and other polymers. Its difunctional nature allows for the formation of complex polymer networks with tailored properties.
Organic Synthesis Intermediate
It acts as a versatile building block for creating more complex organic molecules. The reactive isocyanate groups can undergo reactions with nucleophiles like alcohols, amines, and water.
Material Science Research
Used in research laboratories for developing novel materials, including specialized coatings, adhesives, and elastomers. Its structure can influence the final properties of the resulting materials.
| Molecular weight | 174.16 |
|---|---|
| Linear formula | CH3C6H3(NCO)2 |
| Assay | 98% |
| Boiling point | 138-139 °C/15 mmHg(lit.) |
| Melting point | 35-39 °C(lit.) |


Hazard statements
- H317May cause an allergic skin reaction
- H330Fatal if inhaled
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 45-46-26-42/43 |
| Safety statements (S) | 53-22-26-28-38-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tolylene 2,5-diisocyanate used for?
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Tolylene 2,5-diisocyanate is primarily used as an intermediate in organic synthesis and for the production of polymers, including polyurethanes, and in material science research.
What is the CAS number and formula for Tolylene 2,5-diisocyanate?
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The CAS number is 614-90-4 and the linear formula is CH₃C₆H₃(NCO)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tolylene 2,5-diisocyanate with a minimum purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should Tolylene 2,5-diisocyanate be handled safely?
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Tolylene 2,5-diisocyanate is a dangerous substance. It is toxic if inhaled and may cause an allergic skin reaction and cancer. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. Seek immediate medical attention if exposed.
How is Tolylene 2,5-diisocyanate packed and shipped?
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Tolylene 2,5-diisocyanate is packed in compliance with UN 2811 6.1 / PGII regulations for hazardous materials. TSS exports this chemical globally.
How can I request a sample or quote for Tolylene 2,5-diisocyanate?
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To request a sample or a quote, please use the 'Request a Quote' button on our website or contact our sales team directly with your specific requirements.
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