3-Amino-5-tert-butylisoxazole
3-Amino-5-tert-butylisoxazole (CAS: 55809-36-4) is a heterocyclic organic compound with the molecular formula C7H12N2O and a molecular weight of 140.18 g/mol. It serves as a valuable building block in organic synthesis, particularly within the field of heterocyclic chemistry. This compound is primarily utilised as a reagent in specific amination reactions, contributing to the construction of more complex molecular architectures.
Palladium-Catalyzed Amination
This compound is employed in palladium-catalyzed amination reactions, specifically in the amination of aryl bromides. The process often utilises catalysts such as Pd(dba)₃ and ligands like Xantphos.
Heterocyclic Synthesis
As an isoxazole derivative, it functions as a key building block for synthesising more complex heterocyclic compounds. Its structure lends itself to various derivatisations in advanced organic chemistry.
Research and Development
3-Amino-5-tert-butylisoxazole is utilised in research laboratories for exploring new synthetic routes and developing novel chemical entities. Its specific reactivity profile makes it suitable for targeted chemical transformations.
| Molecular weight | 140.18 |
|---|---|
| Empirical formula | C7H12N2O |
| Assay | 97% |
| Application | Amination of aryl bromides catalyzed by Pd(dba)3 (Aldrich Catalog No. 328774) and Xantphos (Aldrich Catalog No. 526460).1 |
| Melting point | 110-114 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Amino-5-tert-butylisoxazole used for?
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3-Amino-5-tert-butylisoxazole is primarily used as a building block in organic synthesis, particularly for amination reactions of aryl bromides catalysed by palladium complexes, and in the general synthesis of heterocyclic compounds.
What is the CAS number and formula for 3-Amino-5-tert-butylisoxazole?
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The CAS number for 3-Amino-5-tert-butylisoxazole is 55809-36-4, and its empirical formula is C7H12N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Amino-5-tert-butylisoxazole with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 3-Amino-5-tert-butylisoxazole be handled safely?
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3-Amino-5-tert-butylisoxazole is classified as a GHS07 warning substance. It is harmful if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves should be used. Handle in a well-ventilated area and avoid breathing dust.
Is 3-Amino-5-tert-butylisoxazole a controlled substance?
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Based on the provided data, there is no indication that 3-Amino-5-tert-butylisoxazole is a controlled substance.
How is 3-Amino-5-tert-butylisoxazole packed and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all necessary safety and regulatory requirements for international shipping.
How can I request a sample or quote for 3-Amino-5-tert-butylisoxazole?
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To request a sample or a quote for 3-Amino-5-tert-butylisoxazole, please contact our sales team through the website or by phone, providing your details and the product CAS number 55809-36-4.
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