ASB-14
ASB-14 (CAS: 216667-08-2), with the molecular formula C22H46N2O4S and a molecular weight of 434.68 g/mol, is a zwitterionic detergent. It is highly valued for its utility in biological applications, particularly for the solubilisation of proteins, including challenging membrane proteins. Its properties make it an effective choice for preparing samples for 2D electrophoresis and other protein analysis techniques where maintaining protein structure and function is critical.
- IUPAC
- 3-[N,N-Dimethyl(3-myristoylaminopropyl)ammonio]propanesulfonate,Amidosulfobetaine-14
- Synonyms
- 3-[N,N-Dimethyl(3-myristoylaminopropyl)ammonio]propanesulfonateAmidosulfobetaine-14
Protein Solubilisation
ASB-14 is effective in solubilising a broad range of proteins, including hydrophobic membrane proteins. This is crucial for downstream applications such as structural analysis and functional studies.
2D Electrophoresis
As a zwitterionic detergent, ASB-14 is particularly useful for protein solubilisation in preparation for 2D electrophoresis, helping to maintain protein integrity during separation.
Nanodisc Preparations
Its detergent properties make ASB-14 suitable for use in the formation of nanodiscs, which are valuable tools for studying membrane proteins in a near-native lipid environment.
Cell Lysis
ASB-14 can be employed in cell lysis buffers to facilitate the extraction of intracellular proteins, including those that may be associated with cellular membranes.
| Molecular weight | 434.68 |
|---|---|
| Empirical formula | C22H46N2O4S |
| Storage temperature | 2-8°C |
| Application | Zwitterionic detergent. Useful for solubilization of proteins, including membrane proteins, for 2D electrophoresis. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | zwitterionic |
|---|---|
| Mol Wt | average mol wt >10,000 |
| Aggregation Number | ≥23 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ASB-14 used for?
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ASB-14 is primarily used as a zwitterionic detergent for solubilising proteins, including membrane proteins, and is valuable for applications such as 2D electrophoresis, nanodisc preparations, and cell lysis.
What is the CAS number and formula for ASB-14?
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The CAS number for ASB-14 is 216667-08-2, and its molecular formula is C22H46N2O4S.
What grade and purity does Tech Serve Solutions supply for ASB-14?
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Tech Serve Solutions supplies ASB-14 with an average molecular weight indicated. It is not specified as USP, BP, or EP grade. TSS provides this chemical for research and laboratory use.
How should ASB-14 be handled and stored?
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Handle ASB-14 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Store at 2-8°C. The WGK Germany classification is 3, indicating it is hazardous to water.
Is ASB-14 available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including ASB-14.
How can I request a sample or quote for ASB-14?
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Please contact our sales team directly via our website or through your established TSS account channels to request a sample or a quotation for ASB-14.
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