Acepromazine maleate
Acepromazine maleate (CAS: 3598-37-6), with the molecular formula C19H22N2OS · C4H4O4 and a molecular weight of 442.53 g/mol, is a phenothiazine derivative. It functions as a dopamine receptor antagonist and is known to inhibit the ABCG2 transport protein. This yellow powder is primarily utilised in research settings for its pharmacological properties, particularly in studies related to neuroscience and cell signaling.
- IUPAC
- 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate salt,Acepromazine maleate salt,Acetopromazine maleate salt
- Synonyms
- 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate saltAcepromazine maleate saltAcetopromazine maleate salt
Dopamine Receptor Antagonism Research
Acepromazine maleate serves as a valuable tool for investigating the role of dopamine receptors in various biological processes. Its ability to block these receptors aids in understanding neurotransmission and associated neurological pathways.
ABCG2 Transport Protein Inhibition Studies
This compound is employed to study the function and inhibition of the ABCG2 transport protein. Research may focus on its implications in drug resistance and cellular efflux mechanisms.
Neuroscience Research
As a dopaminergic antagonist, Acepromazine maleate is utilized in neuroscience to explore the complexities of the central nervous system and neurochemical signaling.
Cell Biology and Signaling
The inhibition of ABCG2 protein by Acepromazine maleate makes it relevant for cell biology studies, particularly in understanding cell signaling pathways and potential drug resistance mechanisms in cellular models.
| Molecular weight | 442.53 |
|---|---|
| Empirical formula | C19H22N2OS · C4H4O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | H2O: >10 mg/mL |
| Storage temperature | room temp |
| Application | Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine (Cat. No. C8138). Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance. |
Hazard statements
- H302Harmful if swallowed
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Transport (UN / ADR) | UN 3077 9/PG 3 |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 22-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | protect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acepromazine maleate used for?
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Acepromazine maleate is used in research to study dopamine receptor antagonism and the inhibition of the ABCG2 transport protein, contributing to fields like neuroscience and cell biology.
What are the CAS number and formula for Acepromazine maleate?
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The CAS number for Acepromazine maleate is 3598-37-6, and its empirical formula is C19H22N2OS · C4H4O4.
What grade and purity does Tech Serve Solutions supply for Acepromazine maleate?
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Tech Serve Solutions supplies Acepromazine maleate with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
How should Acepromazine maleate be handled safely?
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Acepromazine maleate is harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332). Handle with appropriate personal protective equipment (P280) in a well-ventilated area and avoid ingestion, skin contact, and inhalation.
How is Acepromazine maleate packed and exported?
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Acepromazine maleate is typically supplied as a yellow powder, protected from light, and stored at room temperature. TSS can export this chemical globally, adhering to all relevant shipping regulations, including UN 3077 for transport.
How can I request a quote or sample of Acepromazine maleate?
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To request a quote or sample of Acepromazine maleate, please contact our sales team through the website or by phone. Specify the quantity and your delivery details.
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