4-Chloro-6,8-difluoroquinoline
4-Chloro-6,8-difluoroquinoline (CAS: 239463-89-9), with the molecular formula C9H4ClF2N and a molecular weight of 199.58 g/mol, is a fluorinated heterocyclic compound. It serves as a valuable building block in organic synthesis, particularly for the development of novel pharmaceutical intermediates and advanced materials. Its specific structure, featuring both chlorine and fluorine substituents on a quinoline core, makes it a useful synthon for introducing unique chemical properties into target molecules.
- Synonyms
- C9H4ClF2N

Pharmaceutical Intermediate Synthesis
This compound is employed as a key intermediate in the synthesis of various pharmacologically active compounds. The quinoline scaffold and halogen substituents allow for diverse functionalization pathways in drug discovery.
Material Science
4-Chloro-6,8-difluoroquinoline can be utilised in the development of novel materials, including functional polymers and organic electronic components. Its fluorinated nature can impart desirable properties such as thermal stability and specific electronic characteristics.
Agrochemical Research
The unique structure of this molecule makes it a potential candidate for research in the agrochemical sector, where halogenated heterocycles are often explored for their biological activity.
Organic Synthesis Building Block
As a versatile building block, it facilitates the creation of complex organic molecules. Researchers can leverage its reactive sites for further chemical transformations, leading to a wide array of target compounds.
| Molecular weight | 199.58 |
|---|---|
| Empirical formula | C9H4ClF2N |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-6,8-difluoroquinoline used for?
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4-Chloro-6,8-difluoroquinoline is primarily used as a building block in organic synthesis for creating pharmaceutical intermediates and advanced materials. It is also explored in agrochemical research.
What is the CAS number and formula for 4-Chloro-6,8-difluoroquinoline?
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The CAS number for 4-Chloro-6,8-difluoroquinoline is 239463-89-9, and its empirical formula is C9H4ClF2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-6,8-difluoroquinoline as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeial standard unless explicitly stated in the product specifications.
How should 4-Chloro-6,8-difluoroquinoline be handled safely?
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4-Chloro-6,8-difluoroquinoline is classified as dangerous. It is harmful if swallowed (H302) and causes serious eye damage (H318). Always wear protective gloves, eye protection, and face protection (P280, P305+P351+P338). In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
Is 4-Chloro-6,8-difluoroquinoline a controlled substance?
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The provided data does not indicate that 4-Chloro-6,8-difluoroquinoline is a controlled substance.
How is 4-Chloro-6,8-difluoroquinoline packed and shipped?
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4-Chloro-6,8-difluoroquinoline is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical products.
How can I request a quote or sample?
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To request a quote or sample of 4-Chloro-6,8-difluoroquinoline, please contact the Tech Serve Solutions sales team through our official website or listed contact details.
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