Acetazolamide

CAS 59-66-5C4H6N4O3S2Biochemicals & Reagents

Acetazolamide (CAS: 59-66-5), with the molecular formula C4H6N4O3S2 and a molecular weight of 222.25 g/mol, is a fine chemical powder. It functions as a carbonic anhydrase inhibitor and is known to increase cerebral blood flow. This compound is widely utilised in research and laboratory settings for biochemical studies and as an enzyme inhibitor.

IUPAC: 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide,N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide,N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide
Synonyms: N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide5-Acetamido-1,3,4-thiadiazole-2-sulfonamideN-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide

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Acetazolamide (C4H6N4O3S2) — chemical structure, CAS 59-66-5; Life Science, fine chemical supplied by Tech Serve Solutions

A to CA-AMBioactive Small MoleculesBiochemicals and ReagentsCarbonic anhydraseCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitors

01 /Applications

Carbonic Anhydrase Inhibition

Acetazolamide acts as a potent inhibitor of carbonic anhydrase enzymes. This activity is fundamental to its use in various biochemical and physiological research applications.

Cerebral Blood Flow Modulation

The compound is recognized for its effect in increasing cerebral blood flow. This characteristic makes it a subject of interest in neurological and physiological research studies.

Enzyme Inhibitor Research

As a well-established enzyme inhibitor, Acetazolamide is employed in laboratory settings to study enzyme kinetics and mechanisms, particularly those involving carbonic anhydrase.

02 /Properties

Molecular weight	222.25
Empirical formula	C4H6N4O3S2
Assay	≥99%
Form	powder
Solubility	1 M NH4OH: soluble50 mg/mLDMSO: solublemethanol and ethanol: slightly soluble
Application	Carbonic anhydrase inhibitor; increases cerebral blood flow.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xi
Risk statements (R)	36/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

59-66-5

MDL number

MFCD00003105

PubChem substance

24278144

05 /Additional specifications

Pka	7.2

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Acetazolamide primarily used for?

Acetazolamide is primarily used as a carbonic anhydrase inhibitor and to increase cerebral blood flow in research settings.

What is the CAS number and formula for Acetazolamide?

The CAS number for Acetazolamide is 59-66-5, and its molecular formula is C4H6N4O3S2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Acetazolamide with an assay of ≥99%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.

How should Acetazolamide be handled safely?

Acetazolamide is a 'Warning' substance (GHS07) that can cause skin (H315) and serious eye irritation (H319). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).

How is Acetazolamide packed and exported?

Acetazolamide is available as a powder and is carefully packed for shipment and export by Tech Serve Solutions, adhering to all necessary regulations for chemical handling and transport.