4-(tert-Butyldimethylsilyloxy)-1-butyne
4-(tert-Butyldimethylsilyloxy)-1-butyne (CAS 78592-82-2), with the linear formula CH≡C(CH2)2OSi(CH3)2C(CH3)3 and a molecular weight of 184.35 g/mol, is a valuable organic building block. This terminal alkyne features a silyl-protected hydroxyl group, making it useful in complex organic synthesis for introducing specific functionalities. Its reactivity allows for participation in various coupling reactions and functional group transformations.
Organic Synthesis Intermediate
Utilised as a key intermediate in the multi-step synthesis of complex organic molecules. The protected alkyne and hydroxyl functionalities allow for selective chemical transformations.
Building Block for Heterocycles
Serves as a versatile building block in the construction of various heterocyclic compounds, which are important scaffolds in medicinal chemistry.
Research and Development
Employed in academic and industrial research laboratories for exploring new synthetic methodologies and developing novel chemical entities.
| Molecular weight | 184.35 |
|---|---|
| Linear formula | CH≡C(CH2)2OSi(CH3)2C(CH3)3 |
| Assay | 97% |
| Boiling point | 70-74 °C/10 mmHg(lit.) |
| Density | 0.893 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.43(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(tert-Butyldimethylsilyloxy)-1-butyne used for?
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This compound is primarily used as an intermediate and building block in organic synthesis, particularly for constructing complex molecules and heterocyclic compounds in research and development.
What are the CAS number and chemical formula?
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The CAS number is 78592-82-2 and the linear chemical formula is CH≡C(CH2)2OSi(CH3)2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This chemical is flammable (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation.
How is 4-(tert-Butyldimethylsilyloxy)-1-butyne typically packed and shipped?
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Products are packed according to relevant regulations for hazardous materials. We export globally, adhering to all international shipping standards.
How can I request a sample or a quote?
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To request a sample or a quote, please contact our sales department via the website or direct email, providing your required quantity and shipping details.
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