4-(tert-Butyldimethylsilyl)oxy-1-butanol

CAS 87184-99-4(CH3)3CSi(CH3)2O(CH2)4OHChemical Synthesis

4-(tert-Butyldimethylsilyl)oxy-1-butanol (CAS 87184-99-4) is a silyl ether alcohol with a molecular weight of 204.38. This organic building block serves as a versatile intermediate in chemical synthesis. It is particularly useful in organic chemistry for introducing protected hydroxyl functionalities, enabling complex molecule construction. Supplied by Tech Serve Solutions, it is available at a minimum assay of 97%.

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4-(tert-Butyldimethylsilyl)oxy-1-butanol ((CH3)3CSi(CH3)2O(CH2)4OH) — chemical structure, CAS 87184-99-4; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsBuilding BlocksC9 to C10Chemical SynthesisOrganic Building BlocksOxygen Compounds More...

01 /Applications

Organic Synthesis Intermediate

This compound functions as a valuable building block in multi-step organic syntheses. The tert-butyldimethylsilyl (TBDMS) protecting group on the alcohol allows for selective reactions at other sites of a molecule before deprotection.

Protecting Group Chemistry

The TBDMS ether functionality is widely employed to protect primary alcohols during various chemical transformations. Its stability under a range of reaction conditions and straightforward removal make it a preferred choice in synthetic planning.

Pharmaceutical Intermediates

It can be utilised in the synthesis pathways of complex pharmaceutical active ingredients (APIs) where controlled introduction and manipulation of hydroxyl groups are required.

02 /Properties

Molecular weight	204.38
Linear formula	(CH3)3CSi(CH3)2O(CH2)4OH
Assay	97%
Boiling point	63-66 °C/0.3 mmHg(lit.)
Density	0.888 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.4390(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	105 °C / 221 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

87184-99-4

MDL number

MFCD04974070

PubChem substance

24880450

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(tert-Butyldimethylsilyl)oxy-1-butanol used for?

4-(tert-Butyldimethylsilyl)oxy-1-butanol is used as a versatile building block in organic synthesis, particularly for introducing protected hydroxyl groups, and can serve as an intermediate in the preparation of pharmaceuticals.

What is the CAS number and formula for 4-(tert-Butyldimethylsilyl)oxy-1-butanol?

The CAS number is 87184-99-4. The linear formula is (CH3)3CSi(CH3)2O(CH2)4OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-(tert-Butyldimethylsilyl)oxy-1-butanol at an assay of 97%. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product data.

What are the safety and handling precautions for this chemical?

This compound is combustible with a flash point of 105 °C (221 °F). When handling, it is essential to wear safety eyeshields and gloves. Appropriate respiratory protection, such as a half-mask respirator, should be used.

How is this chemical shipped or exported?

Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export details for 4-(tert-Butyldimethylsilyl)oxy-1-butanol are available upon request, adhering to all relevant regulations.