4-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester
4-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester (CAS: 480438-75-3) is an organoboron compound with a molecular weight of 320.19 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure features a phenylboronic acid pinacol ester moiety protected with a tert-butoxycarbonyl group, enabling its use in pharmaceutical and agrochemical research and development.
- IUPAC
- tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl Carbonate
Suzuki-Miyaura Coupling Reagent
This compound is extensively employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds, a fundamental transformation in the synthesis of complex organic molecules, including pharmaceuticals and advanced materials.
Intermediate in Pharmaceutical Synthesis
Its functional groups make it a strategic intermediate for constructing diverse molecular architectures. It is utilised in the synthesis of active pharmaceutical ingredients (APIs) and their precursors, contributing to drug discovery and development pipelines.
Building Block for Organic Synthesis
The presence of the boronate ester and the protected phenol allows for regioselective functionalization. This makes it a versatile building block for creating novel chemical entities in academic and industrial research settings.
| Molecular weight | 320.19 |
|---|---|
| Linear formula | C6H4OCOOC(CH3)3C2BO2(CH3)4 |
| Assay | 97% |
| Melting point | 107-111 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester used for?
+
This compound is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions and as a versatile building block in organic synthesis for the creation of complex molecules, including pharmaceutical intermediates.
What is the CAS number and molecular formula for this compound?
+
The CAS number is 480438-75-3. The linear formula is C<sub>6</sub>H<sub>4</sub>OCOOC(CH<sub>3</sub>)<sub>3</sub>C<sub>2</sub>BO<sub>2</sub>(CH<sub>3</sub>)<sub>4</sub>.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical at a purity of 97% (assay). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
+
Users should wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. The compound is classified with WGK 2 in Germany, indicating a moderate hazard to water.
How is this chemical packed and shipped?
+
Tech Serve Solutions exports this chemical globally. Packaging is designed to ensure product integrity during transit, adhering to international shipping regulations for chemical substances.
How can I request a quote or sample?
+
To request a quote or a sample, please contact our sales department through the details provided on our website. We will respond promptly to your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis