4-(p-Iodophenyl)butyric acid
4-(p-Iodophenyl)butyric acid (CAS: 27913-58-2, Formula: C10H11IO2) is a versatile organic compound with a molecular weight of 290.10. Supplied by Tech Serve Solutions with an assay of ≥98%, this compound serves as a key building block in organic synthesis. It is particularly noted for its role in the construction of complex molecular architectures, including cyclophanes and tetralones, and in research exploring the pharmacological activities of novel therapeutic agents.
- IUPAC
- 4-Iodobenzenebutanoic acid
- Synonyms
- 4-Iodobenzenebutanoic acid

Synthesis of Cyclophanes and Tetralones
This compound is utilized as a reactant in the synthesis of meta- and paracyclophanes featuring unsaturated amino acids. It also plays a role in intramolecular Friedel-Crafts reactions, facilitating the synthesis of 1-tetralones.
Pharmacological Research
4-(p-Iodophenyl)butyric acid is involved in investigations into the pharmacological activity related to apoptosis, proliferation, and histone deacetylase activity in human colorectal cancer cells. It is also part of research concerning portable albumin binders for extending the half-life of contrast agents.
Organic Synthesis Building Block
As a functionalized carboxylic acid containing an aryl iodide, it is a valuable building block for introducing the 4-(p-iodophenyl)butyryl moiety into larger molecules. This enables further derivatization through reactions involving the carboxylic acid or the aryl iodide.
| Molecular weight | 290.10 |
|---|---|
| Empirical formula | C10H11IO2 |
| Assay | ≥98% |
| Storage temperature | 2-8°C |
| Application | Reactant involved in:• Synthesis of meta- and paracyclophanes containing unsaturated amino acids1• Intramolecular Friedel-Crafts reactions for synthesis of 1-tetralones2Involved in investigations of pharmacological activity pertaining to:• Apoptosis, proliferation, and histon deacetylase activity in human colorectal cancer cells3,4• Portable albumin binders for extending the half-life of contrast agents5 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(p-Iodophenyl)butyric acid used for?
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4-(p-Iodophenyl)butyric acid is primarily used as a building block in organic synthesis, including the preparation of cyclophanes and tetralones. It is also employed in research investigating pharmacological activities, such as those related to cancer cell biology and the development of albumin binders for contrast agents.
What is the CAS number and formula for 4-(p-Iodophenyl)butyric acid?
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The CAS number for 4-(p-Iodophenyl)butyric acid is 27913-58-2, and its molecular formula is C10H11IO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(p-Iodophenyl)butyric acid with a purity of ≥98%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 4-(p-Iodophenyl)butyric acid be handled and stored?
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Handle 4-(p-Iodophenyl)butyric acid with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at 2-8°C.
Is 4-(p-Iodophenyl)butyric acid a controlled substance?
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The provided data does not indicate that 4-(p-Iodophenyl)butyric acid is a controlled substance.
How is 4-(p-Iodophenyl)butyric acid packed, shipped, and exported?
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Tech Serve Solutions, a specialist global supplier and exporter, ensures appropriate packaging and adherence to regulations for the shipment and export of 4-(p-Iodophenyl)butyric acid.
How can I request a sample or quote for 4-(p-Iodophenyl)butyric acid?
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To request a sample or quote for 4-(p-Iodophenyl)butyric acid, please contact the Tech Serve Solutions sales team through the provided channels on our website.
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