4-(tert-Butyldimethylsiloxy)phenol
4-(tert-Butyldimethylsiloxy)phenol (CAS: 108534-47-0), with the molecular formula C12H20O2Si and a molecular weight of 224.37 g/mol, is a valuable organic building block. This silyl-protected phenol derivative serves as a key intermediate in complex organic synthesis. Its applications are primarily found in research and development laboratories, and it is supplied by Tech Serve Solutions with a minimum assay of 97%.

Organic Synthesis Intermediate
This compound functions as a protected phenol in multi-step organic syntheses. The tert-butyldimethylsilyl (TBDMS) group provides robust protection for the phenolic hydroxyl, allowing selective reactions elsewhere in the molecule. It is commonly employed in the synthesis of pharmaceuticals and complex organic molecules.
Research and Development
As a versatile building block, 4-(tert-Butyldimethylsiloxy)phenol is utilised in academic and industrial research settings for exploring novel chemical pathways and developing new materials or drug candidates.
Preparation of Advanced Materials
The compound can be incorporated into the synthesis of functionalised polymers or other advanced materials where a protected phenolic moiety is required for subsequent modification or to impart specific properties.
| Molecular weight | 224.37 |
|---|---|
| Empirical formula | C12H20O2Si |
| Assay | 97% |
| Melting point | 60-64 °C(lit.) |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(tert-Butyldimethylsiloxy)phenol used for?
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4-(tert-Butyldimethylsiloxy)phenol is used as a protected phenol intermediate in organic synthesis, particularly in the development of pharmaceuticals and complex organic molecules.
What are the CAS number and formula for this chemical?
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The CAS number is 108534-47-0 and the molecular formula is C12H20O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(tert-Butyldimethylsiloxy)phenol with a minimum assay of 97%. This is a technical/research grade; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety hazards associated with 4-(tert-Butyldimethylsiloxy)phenol?
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This compound is classified as Danger, with hazard statement H318, indicating it causes serious eye damage. Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be worn during handling.
How is 4-(tert-Butyldimethylsiloxy)phenol packed and exported?
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4-(tert-Butyldimethylsiloxy)phenol is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a sample or quote for 4-(tert-Butyldimethylsiloxy)phenol?
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To request a sample or a quote, please contact our sales team through the website or by calling our office, providing the product name and CAS number.
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