Amiodarone hydrochloride
Amiodarone hydrochloride (CAS: 19774-82-4), with the empirical formula C25H29I2NO3 · HCl and a molecular weight of 681.77 g/mol, is a potent non-selective ion channel blocker. It is recognised for its broad fungicidal activity, inducing Ca2+ influx and subsequent cell death in yeast. This compound also finds application in environmental studies for detecting thyroid-disrupting substances.
- IUPAC
- (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride,2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride
- Synonyms
- (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride
Fungicidal Activity Studies
Amiodarone hydrochloride exhibits broad fungicidal activity, notably inducing Ca2+ influx and mitochondrial fragmentation leading to cell death in yeast models. This makes it a valuable reagent for studying fungal cell death mechanisms.
Environmental Analysis
This compound has been utilised in research to quantify thyroid-disrupting substances within wastewater treatment plant effluents. Its specific chemical properties allow for its use as an analytical standard in such environmental monitoring studies.
Ion Channel Research
As a non-selective ion channel blocker, amiodarone hydrochloride is employed in biochemical research to investigate ion channel function and its impact on cellular processes. It serves as a tool for understanding cellular signalling pathways.
| Molecular weight | 681.77 |
|---|---|
| Empirical formula | C25H29I2NO3 · HCl |
| Assay | ≥98% |
| Storage temperature | 2-8°C |
| Application | Amiodarone hydrochloride is a non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death. Amiodarone hydrochloride has also been used in a study to determine concentrations of thyroid disrupting substances in effluents from wastewater treatment plants. |
Hazard statements
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Amiodarone hydrochloride used for?
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Amiodarone hydrochloride is used for its broad fungicidal activity, particularly in yeast, and in environmental studies to detect thyroid-disrupting substances. It also serves as a non-selective ion channel blocker in research.
What is the CAS number and formula for Amiodarone hydrochloride?
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The CAS number for Amiodarone hydrochloride is 19774-82-4, and its empirical formula is C25H29I2NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Amiodarone hydrochloride with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How should Amiodarone hydrochloride be handled safely?
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Amiodarone hydrochloride is classified as a Warning substance with hazards H312 (Harmful in contact with skin) and H332 (Harmful if inhaled). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves.
How is Amiodarone hydrochloride packaged and shipped?
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Amiodarone hydrochloride is stored at 2-8°C. We expertly pack and export fine chemicals globally.
How can I request a sample or quote for Amiodarone hydrochloride?
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To request a sample or obtain a quote, please contact our customer service team through the website or by phone.
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