7-Hydroxy-4-methyl-3-coumarinylacetic acid
7-Hydroxy-4-methyl-3-coumarinylacetic acid (CAS 5852-10-8), with the molecular formula C12H10O5 and a molecular weight of 234.20 g/mol, is a valuable biochemical and reagent. It is particularly noted for its utility as a fluorescent indicator and probe, owing to its distinct fluorescent properties. This compound serves in various detection and labeling applications within scientific research and laboratory settings.
- IUPAC
- 4-Methylumbelliferone-3-acetic acid
- Synonyms
- 4-Methylumbelliferone-3-acetic acid

Fluorescent Indicator
This compound functions effectively as a fluorescent indicator, suitable for fluorescence-based detection methods. Its spectral properties allow for visual or instrumental monitoring in various assays.
pH Indicator
With specific application as a pH indicator, 7-Hydroxy-4-methyl-3-coumarinylacetic acid can be employed to monitor and signal changes in acidity or alkalinity within a solution.
Fluorescent Labeling
Its fluorescent nature makes it useful as a label in biological and chemical research. It can be incorporated into molecules or structures to enable their detection and study using fluorescence microscopy or spectroscopy.
| Molecular weight | 234.20 |
|---|---|
| Empirical formula | C12H10O5 |
| Assay | ≥98.0% (HPLC) |
| Solubility | DMF: solubleDMSO: soluble |
| Application | suitable as pH-indicator |
| Suitability | suitable for fluorescence |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 360 nm; λem ~450 nm in 0.1 M Tris pH 9.0 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Hydroxy-4-methyl-3-coumarinylacetic acid used for?
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7-Hydroxy-4-methyl-3-coumarinylacetic acid is used as a fluorescent indicator, a pH indicator, and as a fluorescent label in various biochemical and detection applications.
What are the CAS number and formula for 7-Hydroxy-4-methyl-3-coumarinylacetic acid?
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The CAS number is 5852-10-8 and the empirical formula (Hill notation) is C12H10O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98.0% by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 7-Hydroxy-4-methyl-3-coumarinylacetic acid?
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This compound is classified with GHS07 and a Warning signal word. It carries hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 7-Hydroxy-4-methyl-3-coumarinylacetic acid packed and exported?
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Tech Serve Solutions expertly packs and ships fine chemicals globally, adhering to all necessary regulations for international export.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation for 7-Hydroxy-4-methyl-3-coumarinylacetic acid, please contact our sales team via the website or by phone.
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