7-Hydroxy-4-methyl-3-coumarinylacetic acid N-succinimidyl ester
7-Hydroxy-4-methyl-3-coumarinylacetic acid N-succinimidyl ester (CAS 96735-88-5) is a chemical compound with the formula C16H13NO7 and a molecular weight of 331.28 g/mol. Supplied by Tech Serve Solutions for fluorescence applications, this succinimidyl ester derivative of 4-methylumbelliferone-3-acetic acid is designed for labelling biomolecules. Its reactive N-succinimidyl ester group readily forms stable amide bonds with primary amines, making it a valuable tool in biochemical research and diagnostics.
- IUPAC
- 4-Methylumbelliferone-3-acetic acid N-succinimidyl ester,N-Succinimidyl 7-hydroxy-4-methyl-3-coumarinylacetate
- Synonyms
- N-Succinimidyl 7-hydroxy-4-methyl-3-coumarinylacetate4-Methylumbelliferone-3-acetic acid N-succinimidyl ester
Fluorescent Labelling
This compound serves as a fluorescent label, enabling the detection and quantification of molecules containing primary amine groups. The N-succinimidyl ester moiety reacts efficiently with amines to form stable amide linkages, thereby conjugating the coumarin fluorophore to peptides, proteins, or other amine-bearing substrates.
Bioconjugation Reagent
As a bioconjugation reagent, it facilitates the covalent attachment of a fluorescent tag to biomolecules. This is crucial for various biological assays, imaging techniques, and diagnostic applications where fluorescent readouts are required for sensitivity and specificity.
Spectroscopic Analysis
The inherent fluorescence properties of the coumarin structure (λex 322 nm; λem 452 nm) make this ester suitable for use in spectroscopic analysis. It can be employed in functional group labelling for spectroscopy, particularly for membrane research and other lipophilic studies.
| Molecular weight | 331.28 |
|---|---|
| Empirical formula | C16H13NO7 |
| Assay | ≥90.0% |
| Grade | for fluorescence |
| Solubility | DMF: solubleacetonitrile: solublechloroform: soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 322 nm; λem 452 nm in 0.1 M phosphate pH 7.0 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Hydroxy-4-methyl-3-coumarinylacetic acid N-succinimidyl ester used for?
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This compound is primarily used as a fluorescent label and bioconjugation reagent for labelling biomolecules that contain primary amine groups. It is also applied in spectroscopic analysis due to its fluorescent properties.
What are the CAS number and formula for this product?
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The CAS number is 96735-88-5 and the empirical formula is C16H13NO7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for fluorescence applications with an assay of ≥90.0%.
How should this chemical be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store at -20°C. This compound has a WGK Germany classification of 3, indicating it is hazardous.
Is this compound a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is the product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to international shipping and export regulations.
How can I request a sample or quote for this chemical?
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Please contact our sales team through the website to request a sample or a quote for 7-Hydroxy-4-methyl-3-coumarinylacetic acid N-succinimidyl ester.
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