7,8-Dihydroxycoumarin
7,8-Dihydroxycoumarin (CAS: 486-35-1), also known as Daphnetin, is a naturally occurring phenolic compound with the molecular formula C9H6O4 and a molecular weight of 178.14 g/mol. This compound possesses significant antioxidant and anti-inflammatory properties, making it a valuable intermediate in organic synthesis and a subject of research in various biochemical applications. It is primarily utilised as a building block in chemical synthesis and as a fluorescent label.
- IUPAC
- Daphnetin
- Synonyms
- Daphnetin7,8-Dihydroxy-2H-chromen-2-one

Chemical Synthesis Intermediate
7,8-Dihydroxycoumarin serves as a key building block in the synthesis of more complex organic molecules. Its reactive hydroxyl groups allow for diverse chemical modifications, facilitating the development of novel compounds for research and industrial applications.
Biochemical Research
Due to its inherent biological activity, including antioxidant and anti-inflammatory effects, 7,8-Dihydroxycoumarin is utilised in biochemical studies. It can be employed as a reference standard or a starting material for investigating the mechanisms of action of coumarin derivatives.
Fluorescent Probes and Labels
The coumarin scaffold is known for its fluorescence properties. 7,8-Dihydroxycoumarin can be incorporated into molecular probes or used as a fluorescent label for biological imaging and diagnostic assays, aiding in the detection and visualisation of specific cellular components or processes.
| Molecular weight | 178.14 |
|---|---|
| Empirical formula | C9H6O4 |
| Assay | 90% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7,8-Dihydroxycoumarin used for?
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7,8-Dihydroxycoumarin is primarily used as an intermediate in chemical synthesis, a building block for creating more complex molecules, and in biochemical research, including its use as a fluorescent label and probe.
What is the CAS number and formula for 7,8-Dihydroxycoumarin?
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The CAS number for 7,8-Dihydroxycoumarin is 486-35-1, and its molecular formula is C9H6O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7,8-Dihydroxycoumarin with a minimum assay of 90%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety considerations when handling 7,8-Dihydroxycoumarin?
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Handling 7,8-Dihydroxycoumarin requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 2.
Is 7,8-Dihydroxycoumarin a controlled substance?
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Based on the provided data, 7,8-Dihydroxycoumarin (CAS: 486-35-1) is not indicated as a controlled substance.
How is 7,8-Dihydroxycoumarin typically packed and shipped by TSS?
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Tech Serve Solutions professionally packs and exports fine chemicals, including 7,8-Dihydroxycoumarin, adhering to international shipping regulations to ensure safe transit.
How can I request a sample or a quote for 7,8-Dihydroxycoumarin?
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To request a sample or a quote for 7,8-Dihydroxycoumarin, please contact our sales team through the website or by phone.
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