7,8-Dihydroxy-4-methylcoumarin
7,8-Dihydroxy-4-methylcoumarin (CAS 2107-77-9) is a heterocyclic organic compound with the molecular formula C10H8O4 and a molecular weight of 192.17 g/mol. This coumarin derivative functions as a useful fluorescent sensor, particularly for monitoring boronic acid consumption in Suzuki cross-coupling reactions. Its fluorescence is readily observable under a standard long-wave UV lamp, making it a practical tool in synthetic chemistry laboratories.
- IUPAC
- 4-Methyldaphnetin
- Synonyms
- 4-Methyldaphnetin7,8-Dihydroxy-4-methyl-2H-chromen-2-one
Fluorescent Sensor in Cross-Coupling Reactions
7,8-Dihydroxy-4-methylcoumarin serves as an effective fluorescent probe for tracking the progress of Suzuki cross-coupling reactions. It specifically monitors the consumption of boronic acid, a key reactant in these transformations. The compound's fluorescence is easily visualised with a 365 nm UV lamp.
Synthetic Intermediate
As a functionalised coumarin, this compound can be employed as a building block in the synthesis of more complex organic molecules. Its dihydroxy and methyl substituents offer sites for further chemical modification.
Research and Development
This chemical is suitable for use in academic and industrial research settings for exploring new synthetic pathways and developing novel analytical methods. Its properties lend themselves to investigations in organic synthesis and analytical chemistry.
| Molecular weight | 192.17 |
|---|---|
| Empirical formula | C10H8O4 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Can be used as a fluorescent sensor to monitor the consumption of a boronic acid in a Suzuki cross-coupling reaction. Fluorescence is easily detectable to the naked eye using a standard hand-held long-wave UV lamp (365 nm)1. |
| Melting point | 242-246 °C(lit.) |
Hazard statements
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7,8-Dihydroxy-4-methylcoumarin used for?
+
7,8-Dihydroxy-4-methylcoumarin is primarily used as a fluorescent sensor to monitor the consumption of boronic acid in Suzuki cross-coupling reactions. Its fluorescence can be detected using a long-wave UV lamp (365 nm).
What is the CAS number and molecular formula for 7,8-Dihydroxy-4-methylcoumarin?
+
The CAS number for 7,8-Dihydroxy-4-methylcoumarin is 2107-77-9. Its molecular formula is C10H8O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 7,8-Dihydroxy-4-methylcoumarin with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 7,8-Dihydroxy-4-methylcoumarin be handled and stored?
+
This compound is classified as a Danger. It can cause serious eye irritation and may cause allergy or asthma symptoms or breathing difficulties if inhaled. Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, faceshields, and gloves. Store at 2-8°C.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and shipping details are available upon request, adhering to international regulations.
How can I request a sample or quote for 7,8-Dihydroxy-4-methylcoumarin?
+
To request a sample or quote for 7,8-Dihydroxy-4-methylcoumarin, please contact our sales team through the website or by phone. Please reference the CAS number 2107-77-9.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis