4-Bromo-2-fluoro-1-nitrobenzene
4-Bromo-2-fluoro-1-nitrobenzene (CAS 321-23-3) is a chemical compound with the molecular formula C6H3BrFNO2 and a molecular weight of 220.00 g/mol. As an aryl fluorinated building block, it is primarily utilised in organic synthesis, particularly for the construction of complex fused aromatic and heteroaromatic systems. This compound serves as a valuable intermediate in the development of novel chemical entities for research and development purposes.

Synthesis of Fused Aromatic Compounds
4-Bromo-2-fluoro-1-nitrobenzene acts as a key precursor in the synthesis of various fused aromatic ring systems. Its functional groups allow for diverse chemical transformations, enabling the construction of intricate molecular architectures.
Development of Heteroaromatic Structures
This compound is instrumental in the creation of heteroaromatic compounds, which are prevalent in pharmaceuticals and advanced materials. The strategic placement of bromine, fluorine, and nitro groups facilitates targeted derivatisation.
Organic Synthesis Intermediate
As a versatile building block, 4-Bromo-2-fluoro-1-nitrobenzene is employed in multi-step synthetic routes across diverse areas of organic chemistry. Its reactivity profile supports a wide range of coupling and substitution reactions.
| Molecular weight | 220.00 |
|---|---|
| Empirical formula | C6H3BrFNO2 |
| Assay | 95% |
| Application | Building block for fused aromatic and heteroaromatic compounds1 |
| Melting point | 84-88 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluoro-1-nitrobenzene used for?
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4-Bromo-2-fluoro-1-nitrobenzene is primarily used as a building block in organic synthesis for constructing fused aromatic and heteroaromatic compounds.
What is the CAS number and formula for 4-Bromo-2-fluoro-1-nitrobenzene?
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The CAS number is 321-23-3, and the empirical formula is C6H3BrFNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluoro-1-nitrobenzene with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 4-Bromo-2-fluoro-1-nitrobenzene be handled?
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Handle 4-Bromo-2-fluoro-1-nitrobenzene with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US). Avoid breathing dust and ensure adequate ventilation. It is classified as harmful if swallowed, causes skin irritation, eye irritation, and may cause respiratory irritation.
Is 4-Bromo-2-fluoro-1-nitrobenzene a controlled substance?
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The provided data does not indicate that 4-Bromo-2-fluoro-1-nitrobenzene is a controlled substance.
How is 4-Bromo-2-fluoro-1-nitrobenzene packed and shipped?
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4-Bromo-2-fluoro-1-nitrobenzene is carefully packed and exported by Tech Serve Solutions, adhering to relevant shipping regulations for chemical compounds.
How can I request a sample or quote for 4-Bromo-2-fluoro-1-nitrobenzene?
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To request a sample or a quotation for 4-Bromo-2-fluoro-1-nitrobenzene, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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