6-Methoxy-2-pyridinecarboxaldehyde
6-Methoxy-2-pyridinecarboxaldehyde (CAS: 54221-96-4), with the molecular formula C7H7NO2 and a molecular weight of 137.14 g/mol, is a valuable organic building block. This pyridine derivative functions as an aldehyde, suitable for chemical synthesis. It is primarily utilised in the preparation of its corresponding α-pyridoin through treatment with sodium cyanide, serving as a key intermediate in various synthetic pathways.
- IUPAC
- 2-Formyl-6-methoxypyridine,6-Methoxypyridine-2-carbaldehyde
- Synonyms
- 2-Formyl-6-methoxypyridine, 6-Methoxypyridine-2-carbaldehyde
Synthesis of α-Pyridoin
This compound is directly employed in the synthesis of the corresponding α-pyridoin. The reaction typically involves treatment with sodium cyanide, facilitating the formation of the desired coupled product.
Organic Synthesis Intermediate
As a functionalised pyridine, 6-Methoxy-2-pyridinecarboxaldehyde serves as a versatile intermediate in organic synthesis. Its aldehyde group and pyridine core allow for diverse chemical transformations and the construction of more complex molecules.
Heterocyclic Building Block
The molecule's structure, featuring a methoxy-substituted pyridine ring with an aldehyde functionality, makes it a useful building block for creating novel heterocyclic compounds in research and development.
| Molecular weight | 137.14 |
|---|---|
| Empirical formula | C7H7NO2 |
| Assay | 97% |
| Boiling point | 103-104 °C/20 mmHg |
| Density | 1.140 g/mL at 25 °C |
| Refractive index | n20/D 1.532 |
| Application | Synthesis of the corresponding α-pyridoin via treatment with NaCN.1 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Methoxy-2-pyridinecarboxaldehyde used for?
+
It is used as a chemical intermediate for the synthesis of its corresponding α-pyridoin, and as a general building block in organic and heterocyclic synthesis.
What are the CAS number and molecular formula for 6-Methoxy-2-pyridinecarboxaldehyde?
+
The CAS number is 54221-96-4, and the molecular formula is C7H7NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 6-Methoxy-2-pyridinecarboxaldehyde with an assay of 97%. TSS does not represent this product as USP, BP, EP or any other pharmacopoeia grade.
What are the primary safety concerns when handling this chemical?
+
This compound is classified as dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. It may also cause respiratory irritation. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
How is 6-Methoxy-2-pyridinecarboxaldehyde packed and shipped?
+
As a global supplier, Tech Serve Solutions ensures appropriate packaging and shipping methods compliant with international regulations for chemicals like 6-Methoxy-2-pyridinecarboxaldehyde, with a shipping classification of NA 1993 / PGIII.
How can I request a sample or a quote for 6-Methoxy-2-pyridinecarboxaldehyde?
+
Please contact our sales team via our website or direct email to request a sample or obtain a quotation for 6-Methoxy-2-pyridinecarboxaldehyde.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis