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6-Methoxy-2-pyridinylboronic acid MIDA ester

CAS 1227700-45-9C11H13BN2O5Chemical Synthesis

6-Methoxy-2-pyridinylboronic acid MIDA ester (CAS: 1227700-45-9) is a stable organoboron compound with the molecular formula C11H13BN2O5 and a molecular weight of 264.04 g/mol. This MIDA boronate ester serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. Its robust nature and controlled reactivity make it a preferred reagent for introducing the 6-methoxy-2-pyridinyl moiety in complex molecule construction, finding utility in pharmaceutical and materials science research.

IUPAC
2-(6-Methoxy-2-pyridin-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
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6-Methoxy-2-pyridinylboronic acid MIDA ester (C11H13BN2O5) — chemical structure, CAS 1227700-45-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisHeteroaryl MIDA BoronatesMIDA BoronatesOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

This MIDA boronate ester is an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. It is particularly useful for the synthesis of biaryl compounds containing a 6-methoxy-2-pyridinyl unit.

Organic Synthesis Building Block

As a stable and handleable source of the 6-methoxy-2-pyridinyl group, it is employed in the construction of diverse organic molecules. Its MIDA ester form offers enhanced stability compared to the free boronic acid.

Medicinal Chemistry Research

The 6-methoxy-2-pyridinyl motif is present in various biologically active compounds. This reagent facilitates the incorporation of this pharmacologically relevant fragment during drug discovery and development processes.

Materials Science

Organoboron compounds like this MIDA ester can be used in the development of novel materials, including organic light-emitting diodes (OLEDs) and functional polymers, where the pyridine moiety can influence electronic or optical properties.

02 /Properties
Molecular weight264.04
Empirical formulaC11H13BN2O5
Storage temperature2-8°C
Melting point240-246 °C
03 /Identifiers & registry
CAS number
1227700-45-9
MDL number
MFCD16621487
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 6-Methoxy-2-pyridinylboronic acid MIDA ester used for?

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It is primarily used as a stable building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce the 6-methoxy-2-pyridinyl moiety into complex molecules for medicinal chemistry and materials science research.

What is the CAS number and molecular formula for 6-Methoxy-2-pyridinylboronic acid MIDA ester?

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The CAS number is 1227700-45-9, and the molecular formula is C11H13BN2O5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical as research grade. The purity is not specified beyond general analytical standards, and it is not intended for use as USP, BP, or EP grade material.

How should 6-Methoxy-2-pyridinylboronic acid MIDA ester be stored and handled?

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It should be stored at 2-8°C. The compound is classified under WGK 2 (Water Hazard Class 2), indicating it is hazardous to aquatic environments and should be handled with appropriate personal protective equipment to avoid exposure.

Is 6-Methoxy-2-pyridinylboronic acid MIDA ester a controlled substance?

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The provided data does not indicate that 6-Methoxy-2-pyridinylboronic acid MIDA ester is a controlled substance.

How is this chemical packed and exported?

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Tech Serve Solutions packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally. Specific packing details for this product will be provided upon inquiry, adhering to international shipping regulations.

How can I request a sample or quote for 6-Methoxy-2-pyridinylboronic acid MIDA ester?

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Please contact our sales team through the website or by phone to request a sample or a formal quotation. Kindly include the product name and CAS number (1227700-45-9) in your request.

Need 6-Methoxy-2-pyridinylboronic acid MIDA ester in a specific grade or volume?