6-Chloro-3-pyridinylboronic acid MIDA ester
6-Chloro-3-pyridinylboronic acid MIDA ester (CAS: 1257642-71-9) is an organometallic reagent with the molecular formula C10H10BClN2O4 and a molecular weight of 268.46 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its MIDA ester functionality offers enhanced stability and handling properties compared to free boronic acids, making it a preferred choice for researchers and chemists in various synthetic applications.
- IUPAC
- 2-(6-Chloro-3-pyridinyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione,2-Chloropyridine-5-boronic acid MIDA ester,6-Chloro-3-pyridineboronic acid MIDA ester
- Synonyms
- 2-(6-Chloro-3-pyridinyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione2-Chloropyridine-5-boronic acid MIDA ester6-Chloro-3-pyridineboronic acid MIDA ester
Cross-Coupling Reactions
Utilised as a coupling partner in Suzuki-Miyaura reactions and other palladium-catalysed cross-couplings for the formation of carbon-carbon bonds. It is particularly useful for introducing the 6-chloro-3-pyridinyl moiety into complex organic structures.
Heterocyclic Synthesis
Serves as a key intermediate in the synthesis of complex heterocyclic compounds, including pharmaceuticals and agrochemicals. The pyridine ring is a common pharmacophore, and this reagent facilitates its incorporation into larger molecular frameworks.
Organic Synthesis Reagent
A stable and versatile boronate ester that enables precise functionalization of organic molecules. Its well-defined reactivity makes it suitable for multi-step synthetic sequences in academic and industrial research.
| Molecular weight | 268.46 |
|---|---|
| Empirical formula | C10H10BClN2O4 |
| Assay | 97% |
| Melting point | 222-226 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-3-pyridinylboronic acid MIDA ester used for?
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It is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds and the synthesis of heterocyclic compounds.
What are the CAS number and formula for this compound?
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The CAS number is 1257642-71-9, and its molecular formula is C10H10BClN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-3-pyridinylboronic acid MIDA ester with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 6-Chloro-3-pyridinylboronic acid MIDA ester be handled safely?
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This compound is classified as an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet for comprehensive safety information.
Is 6-Chloro-3-pyridinylboronic acid MIDA ester a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is 6-Chloro-3-pyridinylboronic acid MIDA ester typically packed and shipped?
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Tech Serve Solutions exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary shipping regulations. Specific packing details are available upon request.
How can I request a sample or quote for 6-Chloro-3-pyridinylboronic acid MIDA ester?
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You can request a sample or obtain a quote by contacting our sales team through the website or by calling our dedicated customer service line.
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