6-Chloro-4-hydroxy-5-methylpyrimidine
6-Chloro-4-hydroxy-5-methylpyrimidine (CAS: 18261-42-2, Formula: C5H5ClN2O, MW: 144.56) is a heterocyclic organic compound. As a key building block in chemical synthesis, it is particularly useful in the creation of more complex pyrimidine derivatives. Its structure lends itself to applications in medicinal chemistry and materials science, offering a versatile intermediate for research and development purposes.
- IUPAC
- 4-Chloro-6-hydroxy-5-methylpyrimidine,6-Chloro-5-methyl-4-pyrimidinol
- Synonyms
- 4-Chloro-6-hydroxy-5-methylpyrimidine6-Chloro-5-methyl-4-pyrimidinol

Chemical Synthesis Intermediate
This compound serves as a valuable intermediate in organic synthesis, particularly for constructing pyrimidine-based molecules. It is employed in the development of novel heterocyclic compounds with potential biological activities.
Medicinal Chemistry Research
The pyrimidine scaffold is prevalent in many pharmaceuticals. 6-Chloro-4-hydroxy-5-methylpyrimidine can be utilised in the synthesis of potential drug candidates and pharmacologically active agents.
Material Science Development
Functionalised pyrimidines derived from this building block may find applications in material science, such as in the development of organic electronic materials or specialised polymers.
| Molecular weight | 144.56 |
|---|---|
| Empirical formula | C5H5ClN2O |
| Assay | 96% |
| Melting point | 198-203 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-4-hydroxy-5-methylpyrimidine used for?
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6-Chloro-4-hydroxy-5-methylpyrimidine is primarily used as a building block in chemical synthesis, particularly for creating novel pyrimidine derivatives relevant to medicinal chemistry and material science research.
What are the CAS number and formula for 6-Chloro-4-hydroxy-5-methylpyrimidine?
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The CAS number for 6-Chloro-4-hydroxy-5-methylpyrimidine is 18261-42-2, and its molecular formula is C5H5ClN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-4-hydroxy-5-methylpyrimidine with a minimum assay of 96%. This product is typically supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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This compound is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), and causes serious eye damage (H318). Always handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure good ventilation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. P280, P305 + P351 + P338 are key precautionary statements.
Is this chemical controlled or scheduled?
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The provided data does not indicate that 6-Chloro-4-hydroxy-5-methylpyrimidine is a controlled or scheduled substance.
How is 6-Chloro-4-hydroxy-5-methylpyrimidine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed and shipped in compliance with international regulations for hazardous materials.
How can I request a sample or a quote?
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To request a sample or a quote for 6-Chloro-4-hydroxy-5-methylpyrimidine, please contact our sales department through the website or by phone, providing your specific requirements.
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