6-Chloro-5-fluoroindole
6-Chloro-5-fluoroindole (CAS: 122509-72-2) is a fluorinated heterocyclic compound with the molecular formula C8H5ClFN and a molecular weight of 169.58 g/mol. This building block is valuable in organic synthesis, particularly for the construction of complex molecules. Its structure, featuring both chlorine and fluorine substituents on an indole core, makes it a versatile intermediate for developing novel chemical entities in research and development.
- IUPAC
- 6-Chloro-5-fluoro-1H-indole
- Synonyms
- 6-Chloro-5-fluoro-1H-indole

Pharmaceutical Intermediate
Serves as a crucial building block in the synthesis of various pharmaceutical agents, leveraging its fluorinated indole structure for drug discovery and development.
Agrochemical Research
Utilised in the development of new agrochemicals, where the unique properties conferred by the fluoroindole moiety can enhance efficacy and selectivity.
Materials Science
Investigated for its potential use in the synthesis of advanced materials, where its specific electronic and structural properties can be advantageous.
Organic Synthesis Reagent
A versatile reagent for introducing the 6-chloro-5-fluoroindole scaffold into larger molecules during complex organic synthesis projects.
| Molecular weight | 169.58 |
|---|---|
| Empirical formula | C8H5ClFN |
| Assay | 96% |
| Melting point | 103-108 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-5-fluoroindole primarily used for?
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6-Chloro-5-fluoroindole is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 6-Chloro-5-fluoroindole?
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The CAS number for 6-Chloro-5-fluoroindole is 122509-72-2, and its empirical formula is C8H5ClFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-5-fluoroindole at an assay of 96%. This product is supplied for research and laboratory use and is not represented as USP, EP, BP, or pharmaceutical grade.
What are the safety considerations when handling 6-Chloro-5-fluoroindole?
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6-Chloro-5-fluoroindole is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including gloves, eye protection, and in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for comprehensive handling information.
How is 6-Chloro-5-fluoroindole packed, shipped, and exported?
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6-Chloro-5-fluoroindole is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or sample for 6-Chloro-5-fluoroindole?
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To request a quote or a sample of 6-Chloro-5-fluoroindole, please use the contact form on our website or contact our sales team directly with your requirements.
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