5-Methoxy-3-indolylacetonitrile
5-Methoxy-3-indolylacetonitrile (CAS: 2436-17-1, Formula: C11H10N2O, MW: 186.21) is a heterocyclic indole derivative supplied by Tech Serve Solutions. This compound serves as a crucial building block in organic synthesis, particularly for preparing complex molecules. Its applications are found in the research and development of potential therapeutic agents, including enzyme inhibitors and receptor modulators, underscoring its significance in medicinal chemistry and drug discovery.
- IUPAC
- 3-(Cyanomethyl)-5-methoxyindole
Preparation of ChE Inhibitors
It acts as a reactant in synthesising (-)- and (+)-debromoflustramine B and related analogues. These compounds are investigated for their selective inhibition of butyrylcholinesterase.
Synthesis of MAPKAP-K2 Inhibitors
This indole derivative is employed as a starting material for the preparation of carboline analogues. These analogues have demonstrated potent inhibitory activity against MAPKAP-K2.
Development of Aldose Reductase Inhibitors
The compound is utilised in the synthesis of indole-N-acetic acid derivatives. These derivatives are explored for their potential in treating diabetic complications by inhibiting aldose reductase.
Synthesis of Melatoninergic Agonists/Antagonists
It serves as a reactant for preparing phenethyl substituted indole derivatives. These compounds are studied for their activity as melatoninergic agonists and antagonists.
| Molecular weight | 186.21 |
|---|---|
| Empirical formula | C11H10N2O |
| Assay | 95% |
| Application | Reactant for preparation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors1Reactant for preparation of carboline analogs as potent MAPKAP-K2 inhibitors2Reactant for preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment3Reactant for preparation of debromoflustramine B and labeled Me(3a)-13C-physostigmine4Reactant for preparation of physostigmine and physovenine5Reactant for preparation of phenethyl substituted indole derivatives as melatoninergic agonists and antagonists6 |
| Melting point | 65-69 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxy-3-indolylacetonitrile used for?
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5-Methoxy-3-indolylacetonitrile (CAS: 2436-17-1) is primarily used as a building block in organic synthesis. It is a reactant for preparing various compounds, including butyrylcholinesterase inhibitors, MAPKAP-K2 inhibitors, aldose reductase inhibitors, and melatoninergic agonists/antagonists.
What are the CAS number and molecular formula for 5-Methoxy-3-indolylacetonitrile?
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The CAS number for 5-Methoxy-3-indolylacetonitrile is 2436-17-1, and its molecular formula is C11H10N2O.
What grade and purity does Tech Serve Solutions supply for 5-Methoxy-3-indolylacetonitrile?
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Tech Serve Solutions supplies 5-Methoxy-3-indolylacetonitrile with an assay of 95%. This compound is not supplied as USP, BP, or EP grade and is intended for research and laboratory use.
What are the key safety considerations when handling 5-Methoxy-3-indolylacetonitrile?
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When handling 5-Methoxy-3-indolylacetonitrile, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. Consult the Safety Data Sheet for detailed handling and hazard information.
How is 5-Methoxy-3-indolylacetonitrile packed, shipped, and exported?
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5-Methoxy-3-indolylacetonitrile is carefully packed to ensure stability during transit. Tech Serve Solutions, as a global supplier, handles the export of this chemical in compliance with all relevant international regulations.
How can I request a sample or a quote for 5-Methoxy-3-indolylacetonitrile?
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To request a sample or a quote for 5-Methoxy-3-indolylacetonitrile, please contact our sales department through the TSS website or by calling our customer service line. Please specify the required quantity and your delivery location.
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